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Development of sustained-release drug-loaded intravesical inserts via semi-solid micro-extrusion 3D-printing for bladder targeting.
Author: BreitkreutzJörg, FischerBjörn, Rahman-YildirJhinuk
Original Abstract of the Article :
Discontinued treatment and non-adherence are oftentimes weaknesses of common first-line drug therapy against bladder conditions due to their negative side-effects. To overcome these limitations and increase patients' quality of life, intravesical therapies are continuously being explored. 3D-printin...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
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引用元:
https://doi.org/10.1016/j.ijpharm.2022.121849
データ提供:米国国立医学図書館(NLM)
3D-Printed Intravesical Inserts: A New Frontier in Bladder Drug Delivery
The field of [drug delivery] is constantly evolving, seeking more targeted and effective ways to administer medications. This study explores the potential of [3D-printing] to create [sustained-release drug-loaded intravesical inserts] for [bladder targeting]. It's like crafting a miniature desert oasis, a carefully designed structure that delivers a steady stream of medication directly to the bladder.
The researchers used [pressure-assisted micro syringe printing] to create flexible inserts that can be delivered via a [urinary catheter] and remain in place for several weeks. This approach could revolutionize the treatment of [bladder conditions], minimizing side effects and improving patient adherence. It's like finding a new way to irrigate the desert, ensuring that the needed resources reach their destination.
Tailored Drug Delivery: A Personalized Approach
The study demonstrates the versatility of [3D-printing], allowing for customized drug release profiles and geometries. This personalized approach could be a game-changer in [drug delivery], offering targeted treatment tailored to individual patient needs. It's like using a map to navigate a vast desert, creating personalized pathways for optimal drug delivery.
A New Era in Bladder Treatment
The development of [3D-printed intravesical inserts] could significantly improve the management of [bladder conditions], offering a more convenient, targeted, and effective approach to treatment. It's like creating a new oasis in the desert, providing a much-needed respite for patients suffering from bladder problems.
Dr. Camel's Conclusion
This study is a promising step towards the development of a new generation of [drug delivery] systems. The potential of [3D-printing] to create customized [intravesical inserts] for [bladder targeting] is a game-changer, offering a more personalized and effective approach to treatment. It's like using the power of the desert winds to create a new oasis of health and well-being for patients.
Date :
- Date Completed 2022-06-21
- Date Revised 2022-06-21
Further Info :
Related Literature
English
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