Patient perceptions of higher-dose naloxone nasal spray for opioid overdose.

Author: EllisJennifer D, HobelmannJ Gregory, HuhnAndrew S, MarksKatherine R, SmithKirsten E, StricklandJustin C

Paper Details 
Original Abstract of the Article :
Higher-dose formulations of naloxone were recently approved by the FDA for the treatment of opioid overdose. These products were developed based on projected saturation of high-potency fentanyl analogues in the illicit marketplace although the evidence base for their necessity is still under scrutin...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/35636070

データ提供:米国国立医学図書館(NLM)

Navigating the Complexities of High-Dose Naloxone

Opioid overdose is a serious public health concern, and the development of higher-dose formulations of naloxone has brought about a new set of considerations. This research dives into the complex landscape of opioid overdose treatment and explores patient perceptions of these higher-dose formulations. The study highlights the need for greater patient involvement in decision-making processes related to naloxone distribution, particularly considering the potential for increased precipitated withdrawal risk associated with higher doses.

Patient Perspectives are Crucial

This study is the first to provide data on patient perceptions of higher-dose naloxone formulations. The findings indicate that concerns about increased precipitated withdrawal risk are real and must be carefully considered in the context of naloxone distribution efforts. It's a crucial reminder that healthcare decisions should not be made in a vacuum, but rather with the input and understanding of those directly impacted.

A Collaborative Approach to Overdose Prevention

The research suggests that a collaborative approach involving both healthcare professionals and people who use drugs is crucial for navigating the complexities of high-dose naloxone. This collaboration can help ensure that naloxone distribution efforts are effective, safe, and responsive to the needs of the individuals they are intended to help.

Dr.Camel's Conclusion

This research highlights the importance of considering patient perspectives when developing and distributing naloxone formulations. The study underscores the need for a collaborative approach involving both healthcare professionals and people who use drugs to ensure safe and effective overdose prevention strategies. This research is a critical step towards improving the lives of individuals affected by opioid overdose.

Date :
  1. Date Completed 2022-08-15
  2. Date Revised 2023-08-02
Further Info :

Pubmed ID

35636070

DOI: Digital Object Identifier

NIHMS1811308

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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