Paper Details

  1. Home
  2. Paper Details

Citicoline in acute ischemic stroke: A randomized controlled trial.

Author: AgarwalAyush, BhatiaRohit, DwivediSadanand, GargAjay, GoyalVinay, GuptaAnu, RajanRoopa, SharmaJyoti, SinghMamta Bhushan, SrivastavaM V Padma, UpadhyayAshish, VishnuVenugopalan Y

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This study investigated whether giving a medication called citicoline immediately after a procedure to reopen a blocked artery in the brain (recanalization therapy) for stroke would improve outcomes at three months. The study compared citicoline to standard treatment alone, aiming to determine if it could protect the brain from further damage.
Paper Details　
Original Abstract of the Article :
Two pharmacological possibilities exist for an acute ischemic stroke (AIS): recanalization of the occluded artery and neuroprotection from ischaemic injury, the latter's efficacy being debatable. We sought to determine whether administration of Citicoline immediately after recanalization therapy for...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9154187/

データ提供：米国国立医学図書館（NLM）

Citicoline: A Potential Ally in the Battle Against Acute Ischemic Stroke

The [brain] is a complex and delicate organ, and disruptions in its blood supply can have devastating consequences, leading to [acute ischemic stroke]. This study explores the potential benefits of [citicoline], a [neuroprotective agent], in improving outcomes for patients with [acute ischemic stroke]. The authors investigated the effectiveness of [citicoline] in combination with [recanalization therapy], comparing the results to standard treatment alone, and assessing its impact on both [clinical] and [radiological] outcomes.

Citicoline: A New Frontier in Stroke Treatment

The study suggests that [citicoline] may hold promise as a valuable tool in the management of [acute ischemic stroke]. While the results did not show a statistically significant improvement in [clinical outcomes] at [three months], the researchers observed a [positive trend] toward better [radiological outcomes] in the [citicoline] group, suggesting a potential role for [citicoline] in protecting the brain from damage caused by [ischemia].

Navigating the Brain's Delicate Landscape: Citicoline as a Potential Protector

This study offers hope for the development of new therapies to protect the brain from damage caused by [acute ischemic stroke]. The findings suggest that [citicoline] may have a role to play in [neuroprotection], potentially improving [long-term outcomes] for stroke survivors. Further research is needed to fully understand the potential benefits of [citicoline] in this context, but the study provides a promising starting point for future investigations.

Dr.Camel's Conclusion

The [brain] is a complex and delicate organ, and [stroke] can have a devastating impact on a person's life. This study explores the potential of [citicoline] as a neuroprotective agent, offering hope for improved outcomes for stroke survivors. While further research is needed, the study provides a valuable stepping stone in the pursuit of new and effective treatments for this challenging condition.

Date :
  1. Date Completed 2022-06-02
  2. Date Revised 2022-07-16
Further Info :

Pubmed ID

35639720

DOI: Digital Object Identifier

PMC9154187

Related Literature

Article Analysis
・Effective treatment of ischemic stroke
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.