Safety evaluation of oral calcitonin-gene-related peptide receptor antagonists in patients with acute migraine: a systematic review and meta-analysis.

Author: BaekIn-Hwan, HanNayoung, LeeSeoyeon, StaatzChristine E

Paper Details 
Original Abstract of the Article :
Calcitonin gene-related peptide (CGRP) receptor antagonists have been suggested as novel treatments for acute migraine. This study aimed to use meta-analysis to compare the safety and tolerability of five existing oral CGRP receptor antagonists (BI44370TA, MK-3207, rimegepant, telcagepant, and ubrog...See full text at original site
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引用元:
https://doi.org/10.1007/s00228-022-03347-6

データ提供:米国国立医学図書館(NLM)

Navigating the Desert of Migraine: A Review of Oral CGRP Receptor Antagonists

This systematic review and meta-analysis investigates the potential of oral calcitonin gene-related peptide (CGRP) receptor antagonists as a novel treatment for acute migraine. The research is like a desert expedition, seeking safe and effective treatments for a debilitating condition. The study delves into the safety and tolerability of five existing oral CGRP receptor antagonists, comparing them to placebo and triptans. It's a comprehensive assessment, like mapping the intricate landscape of a vast desert.

Promising Results: CGRP Receptor Antagonists for Migraine Relief

The research concluded that oral CGRP receptor antagonists hold promise for migraine treatment. The study found no significant safety concerns and observed positive effects in reducing migraine symptoms. This is like finding a clear path through a desert of pain and suffering, offering hope for individuals struggling with migraine.

Migraine Relief: Exploring New Avenues for Treatment

This research suggests that CGRP receptor antagonists might revolutionize the treatment of migraine. It's like discovering a new oasis in the desert of migraine research, offering a potentially effective and well-tolerated treatment. The findings encourage further research and development of these medications, paving the way for new hope for migraine sufferers.

Dr.Camel's Conclusion

The study on oral CGRP receptor antagonists is a beacon of hope for migraine sufferers. It's a testament to the dedication of researchers who tirelessly work to find solutions for debilitating conditions. This research opens a door to a new era of migraine management, promising relief for millions who experience this debilitating condition.

Date :
  1. Date Completed 2022-08-12
  2. Date Revised 2022-08-12
Further Info :

Pubmed ID

35729340

DOI: Digital Object Identifier

10.1007/s00228-022-03347-6

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Languages

English

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