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Drugs-associated with red man syndrome: An integrative approach using disproportionality analysis and Pharmip.
Author: ChandniVenkumahanti, Lakshmi PrasannaV Marise, M ShajuAina, NairGouri, PanickerNishi, SubeeshViswam
Original Abstract of the Article :
Red man syndrome (RMS) is a non-IgE-mediated anaphylactoid adverse event frequently witnessed after a rapid infusion of vancomycin. This study aims to unravel drugs and associated off-label targets that induce RMS by exploiting FDA Adverse Event Reporting System (FAERS) and Pharmacovigilance/Pharmac...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1111/jcpt.13716
データ提供:米国国立医学図書館(NLM)
Red Man Syndrome: Unveiling the Drugs and Off-Label Targets
Red man syndrome (RMS) is a serious adverse drug reaction that can occur after rapid infusion of vancomycin. This research aims to identify other drugs and associated off-label targets that may induce RMS. The study utilizes data from the FDA Adverse Event Reporting System (FAERS) and the Pharmacovigilance/Pharmacogenomics Insilico Pipeline (PHARMIP) to perform disproportionality analysis. This approach helps identify potential associations between drugs and adverse events, expanding our understanding of RMS and its potential triggers.
Red Man Syndrome: A Desert of Uncertainty
Imagine a camel wandering through a vast and unfamiliar desert, where the dangers are often hidden and unpredictable. In the realm of drug reactions, RMS is like a sandstorm, appearing suddenly and causing discomfort. This research is like a guidebook, helping us navigate this desert of uncertainty by identifying the drugs and targets that may contribute to RMS.
Expanding Our Knowledge of Drug Reactions: A Crucial Step
Understanding the causes of RMS is crucial for improving patient safety and minimizing the risks associated with drug therapy. This study is like a group of camels working together to map out the desert, uncovering new information and expanding our knowledge about RMS and its potential triggers. By identifying other drugs and off-label targets that may induce RMS, we can better manage patient care and prevent this potentially serious adverse drug event.
Dr.Camel's Conclusion
This research provides valuable insights into the potential drugs and targets associated with RMS. It's like finding a new oasis in the desert, offering a fresh perspective and a deeper understanding of this adverse drug reaction. This study underscores the importance of ongoing pharmacovigilance and the need for continuous monitoring of drug safety to ensure that patients receive safe and effective therapies.
Date :
- Date Completed 2022-10-06
- Date Revised 2022-10-06
Further Info :
Related Literature
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