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[High risk localized and locally advanced prostate cancer: Long-term oncological outcomes after prostatectomy].

Author: Batista da CostaJ, De la TailleA, IngelsA, Miro-PadovaniM, SalomonL

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Surgery remains a viable option for treating high-risk localized and locally advanced prostate cancer, showing very good long-term oncological results. A retrospective study of 500 patients demonstrated excellent overall, specific, and biological recurrence-free survival rates at 10 years. However, certain factors like a PSA level ≥20, Gleason score on biopsy ≥9, and MRI stage ≥iT3a were significantly associated with an increased risk of biological recurrence, highlighting the need for careful patient selection for surgery.
Paper Details　
Original Abstract of the Article :
INTRODUCTION: High risk localized and locally advanced forms are responsible for the vast majority of specific deaths from prostate cancer among non-metastatic diseases at diagnosis. No randomized study has yet been published to establish the best local treatment in terms of survival. AIM: Conduct ...See full text at original site
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引用元：
https://doi.org/10.1016/j.purol.2022.04.014

データ提供：米国国立医学図書館（NLM）

Surgical Treatment for High-Risk Prostate Cancer: Long-Term Outcomes

Prostate cancer is a common and often treatable disease, but high-risk localized and locally advanced forms can be more challenging. This study investigates the long-term oncological outcomes of prostatectomy, a surgical procedure to remove the prostate gland, for patients with high-risk localized and locally advanced prostate cancer. The authors analyzed a large cohort of patients who underwent prostatectomy, evaluating their overall survival, specific survival, and biological recurrence-free survival. Their findings offer valuable insights into the effectiveness of prostatectomy as a treatment option for high-risk prostate cancer.

Prostatectomy: A Viable Treatment Option for High-Risk Prostate Cancer

This study demonstrates that prostatectomy can be an effective treatment option for high-risk localized and locally advanced prostate cancer, achieving good long-term oncological results. The study found that patients who underwent prostatectomy had high overall survival and specific survival rates. However, the study also identified certain risk factors that were associated with higher rates of biological recurrence, highlighting the importance of careful patient selection and ongoing surveillance.

Navigating the Treatment of Prostate Cancer

As a doctor, I understand the importance of making informed decisions about prostate cancer treatment. This study offers valuable insights into the effectiveness of prostatectomy for high-risk prostate cancer. It highlights the need for a personalized approach, carefully considering the individual patient's risk factors and treatment goals. It also emphasizes the importance of ongoing surveillance to monitor for potential recurrence.

Dr.Camel's Conclusion

Prostate cancer treatment is like a desert journey, requiring careful planning and navigation. This study is like a guide, helping us understand the effectiveness of prostatectomy for high-risk prostate cancer. By carefully considering the patient's individual circumstances and risk factors, we can make informed decisions to ensure the best possible outcomes.

Date :
  1. Date Completed 2022-08-30
  2. Date Revised 2022-08-30
Further Info :

Pubmed ID

35773175

DOI: Digital Object Identifier

10.1016/j.purol.2022.04.014

Related Literature

Article Analysis
・Effective treatment of prostate cancer
SNS
PICO Info
in preparation
Languages

French

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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