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Voxelotor versus other therapeutic options for sickle cell disease: Are we still lagging behind in treating the disease?

Author: AsgharMuhammad Sohaib, HussainHassan Ul, MalikFarheen, TahirMuhammad Junaid, Tayyaba RehanSyeda, UsamaRana Muhammad

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Limited pharmacological options currently exist for treating sickle cell disease (SCD), highlighting the need for further research and development of new therapies. While hydroxyurea, L-glutamine, crizanlizumab, and voxelotor have shown promise, concerns remain regarding potential side effects and the long-term efficacy of these treatments.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Sickle cell disease (SCD) is one of the most prevalent hemoglobinopathies that affects around 275,000 neonates annually. Until 2017, hydroxyurea was the only available drug for SCD treatment. Later on, L-glutamine and crizanlizumab have shown promising results in SCD therapy. OBJECTIVES...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9213830/

データ提供：米国国立医学図書館（NLM）

The Quest for Effective Sickle Cell Disease Treatment

The field of [hematology] is dedicated to understanding and treating blood disorders such as [sickle cell disease (SCD)]. This article discusses the current state of [SCD treatment] and highlights the need for improved therapeutic options. The authors discuss the limitations of existing treatments, such as [hydroxyurea, L-glutamine, crizanlizumab, and voxelotor], and the need for further research to develop more effective and safe therapies.

Navigating the Challenges of SCD Treatment

The authors emphasize the urgent need for [improved therapeutic options] for [SCD] due to the limitations of existing treatments. They call for more extensive clinical trials to evaluate the efficacy and safety of current and future therapies. This article highlights the ongoing struggle to find effective treatments for this debilitating disease.

Living with Sickle Cell Disease

This article emphasizes the ongoing challenges faced by individuals living with [SCD]. It highlights the importance of continued research efforts to develop more effective and safe treatment options. This article serves as a reminder of the need for improved healthcare access and support for individuals with [SCD].

Dr.Camel's Conclusion

Think of SCD as a desert oasis that faces a constant threat of drought. The quest for effective treatments is like searching for a new water source to sustain this vital oasis. This article underscores the importance of continued research and innovation to provide individuals with SCD the necessary resources to thrive.

Date :
  1. Date Completed n.d.
  2. Date Revised 2022-07-16
Further Info :

Pubmed ID

35774831

DOI: Digital Object Identifier

PMC9213830

Related Literature

Article Analysis
・Side Effects of voxelotor・Effects of voxelotor
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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