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Modified Xiaochaihu Decoction Combined with Mirtazapine in the Treatment of Persistent Depression: A Pilot Randomized Controlled Trial.

Author: GongMan, HeTingting, LiChaoqun, LiJing, LiXin, LiXiuyu, ZhouChao

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

The combination of modified Xiaochaihu Decoction and mirtazapine was more effective in treating PDD than modified Xiaochaihu Decoction alone. The total effective rate of the combined group (96.7%) was significantly higher than the control group (78.6%).
Paper Details　
Original Abstract of the Article :
BACKGROUND: Western drugs effectively manage persistent depressive disorder (PDD) but are associated with side effects. OBJECTIVE: To observe the efficacy and safety of modified Xiaochaihu Decoction combined with mirtazapine in treating PDD. METHODS: Patients with PDD were enrolled at the Naval Ge...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9252686/

データ提供：米国国立医学図書館（NLM）

Persistent Depression: A New Oasis in the Desert of Mental Health

Persistent depressive disorder (PDD), also known as dysthymia, can be a long-lasting and challenging condition to manage. This research explores the efficacy and safety of a combined treatment approach, using modified Xiaochaihu Decoction (a traditional Chinese medicine) alongside mirtazapine (a western antidepressant), in treating PDD.

The study found that the combined treatment group, receiving both modified Xiaochaihu Decoction and mirtazapine, showed significantly better overall clinical efficacy compared to the control group, who received only modified Xiaochaihu Decoction. The combined treatment was also well-tolerated.

Persistent Depression: A Multifaceted Approach to Treatment

This research highlights the potential benefits of integrating traditional Chinese medicine and western medicine approaches in treating PDD. The study suggests that a combined approach may offer a more effective and comprehensive solution for managing this complex condition.

Persistent Depression: Seeking Professional Guidance

If you are experiencing PDD, it's important to consult with a qualified healthcare professional. They can help you develop a personalized treatment plan that considers your individual needs and medical history.

Dr.Camel's Conclusion

This research reminds us that the desert of mental health is vast and complex. By integrating traditional Chinese medicine and western medicine approaches, we may discover new oases of hope and healing for those struggling with persistent depression.

Date :
  1. Date Completed 2022-07-15
  2. Date Revised 2022-08-22
Further Info :

Pubmed ID

35833082

DOI: Digital Object Identifier

PMC9252686

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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