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Vitamin B6 decreases the risk of levetiracetam discontinuation in children with epilepsy: A retrospective study.

Author: BartoliniLuca, Bassell-HawkinsJulia, LobKaren, NieDuyu, PatilRachit

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Levetiracetam (LEV) is an anti-seizure medication that can cause behavioral side effects in children with epilepsy. Our research aims to investigate the relationship between risk factors and LEV side effects, as well as the potential benefits of vitamin B6 in reducing these effects.
Paper Details　
Original Abstract of the Article :
Levetiracetam (LEV) is an anti-seizure medication (ASM) known to have significant behavioral side effects in children with epilepsy. These side effects may be improved by supplemental vitamin B6 (pyridoxine) use. Our research aimed to study risk factors for LEV side effects and the role of vitamin B...See full text at original site
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引用元：
https://doi.org/10.1016/j.yebeh.2022.108839

データ提供：米国国立医学図書館（NLM）

Vitamin B6: A Potential Ally in Managing Levetiracetam Side Effects

This research delves into the complex world of anti-seizure medications (ASMs) and their potential side effects, particularly focusing on levetiracetam (LEV), a commonly prescribed ASM for children with epilepsy. LEV is known for its potential behavioral side effects, which can significantly impact the lives of children and their families. This study explores the role of vitamin B6 in mitigating these side effects.

Vitamin B6: A Potential Solution for Levetiracetam-Related Side Effects

The study suggests that vitamin B6 supplementation may decrease the risk of LEV discontinuation in children with epilepsy. This finding is encouraging, as it offers a potential way to improve LEV tolerability and enhance the effectiveness of treatment for epilepsy. Further research is needed to confirm these findings and determine the optimal dose and duration of vitamin B6 supplementation.

A Holistic Approach to Epilepsy Management

This study highlights the importance of a holistic approach to epilepsy management, considering not only the effectiveness of ASMs but also their potential side effects. The study's findings suggest that vitamin B6 may play a crucial role in optimizing LEV treatment and minimizing the impact of side effects. It is essential to work closely with healthcare professionals to determine the best course of action for individual patients.

Dr.Camel's Conclusion

This study offers a glimmer of hope for children with epilepsy who experience side effects from LEV. Vitamin B6 supplementation may be a valuable tool in mitigating these side effects and improving the overall quality of life for these patients. The study's findings encourage further research into the potential therapeutic benefits of vitamin B6 in epilepsy management, potentially leading to more effective and personalized treatment strategies.

Date :
  1. Date Completed 2022-08-30
  2. Date Revised 2022-11-01
Further Info :

Pubmed ID

35839645

DOI: Digital Object Identifier

10.1016/j.yebeh.2022.108839

SNS
PICO Info
in preparation
Languages

English

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