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Duration of Protection After Vaccination Against Yellow Fever: A Systematic Review and Meta-Analysis.

Author: BogdanChristian, DomingoCristina, DuffySteven, HarderThomas, HowickJeremy, KleijnenJos, KlingKerstin, McDermottKevin, WichmannOle, Wilder-SmithAnnelies, WolffRobert

Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

The duration of protection after a single dose of yellow fever vaccine varies depending on age and immune status. While protection is generally high for healthy individuals, it wanes more quickly in children vaccinated before age 2 and in those with immunodeficiency.
Paper Details　
Original Abstract of the Article :
The duration of protection after a single dose of yellow fever vaccine is a matter of debate. To summarize the current knowledge, we performed a systematic literature review and meta-analysis. Studies on the duration of protection after 1 and ≥2 vaccine doses were reviewed. Data were stratified by t...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9761887/

データ提供：米国国立医学図書館（NLM）

Understanding the Duration of Yellow Fever Vaccine Protection

This study explores the vital question of how long the protection offered by yellow fever vaccine lasts. The research analyzes data from multiple studies to assess the duration of immunity following vaccination, taking into account factors such as age and immune status.

A Detailed Analysis: Assessing the Duration of Vaccine Protection

The meta-analysis revealed that a single dose of yellow fever vaccine provides high levels of protection for several years in healthy adults and children. However, the duration of protection may be shorter in children vaccinated before the age of 2 years and in individuals with compromised immune systems.

The Importance of Vaccination: Protecting Against Yellow Fever

This research highlights the importance of yellow fever vaccination in protecting individuals from this potentially fatal disease. The study emphasizes the need for booster doses in specific populations, such as children vaccinated at a young age and individuals with weakened immune systems, to ensure sustained protection.

Dr.Camel's Conclusion

Imagine a desert where the risk of yellow fever lurks in the shadows. This study, like a beacon of knowledge, illuminates the duration of protection offered by vaccination, guiding us towards effective strategies for preventing this serious disease. The research underscores the vital role of vaccination in safeguarding communities from the dangers of infectious diseases.

Date :
  1. Date Completed 2022-12-21
  2. Date Revised 2023-04-13
Further Info :

Pubmed ID

35856638

DOI: Digital Object Identifier

PMC9761887

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SNS
PICO Info
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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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