Sedative and cardiopulmonary effects of intramuscular combinations of hydromorphone, acepromazine, dexmedetomidine, and glycopyrrolate followed by intravenous propofol and inhalant isoflurane anesthesia in healthy dogs.

Author: HectorRachel C, HessAnn M, KramerBrittany M, MamaKhursheed R, RezendeMarlis L

Paper Details 
Original Abstract of the Article :
OBJECTIVE: To evaluate the sedative and cardiopulmonary effects of various combinations of acepromazine, dexmedetomidine, hydromorphone, and glycopyrrolate, followed by anesthetic induction with propofol and maintenance with isoflurane in healthy dogs. ANIMALS: 6 healthy adult female Beagles. PROC...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/35973002

データ提供:米国国立医学図書館(NLM)

A Tailored Approach to Anesthesia in Canines: Finding the Right Sedative Cocktail

The field of veterinary medicine is constantly seeking to improve the welfare of animals under our care, particularly during surgical procedures. This study focuses on optimizing anesthesia protocols for dogs, aiming to find the ideal combination of sedatives that ensures both effective sedation and minimal adverse effects. The researchers conducted a controlled study involving healthy beagles, comparing various combinations of acepromazine, dexmedetomidine, hydromorphone, and glycopyrrolate. These drugs are commonly used as pre-anesthetics to calm the animal before the administration of general anesthesia. The researchers meticulously monitored the dogs' physiological responses to each combination, measuring heart rate, blood pressure, and other vital signs. This meticulous approach allowed them to identify the most favorable combination that provided effective sedation while maintaining optimal cardiovascular function.

A Winning Formula for Canine Anesthesia

The study found that a specific combination of hydromorphone, acepromazine, dexmedetomidine, and glycopyrrolate (HADG) provided the most favorable outcome, leading to acceptable cardiopulmonary function without any adverse effects. This finding is significant because it provides a safer and more effective approach to pre-anesthesia in dogs, minimizing potential complications and improving overall patient well-being.

Ensuring Canine Comfort and Safety During Procedures

The findings of this study provide valuable insights for veterinarians and animal care professionals. By utilizing the HADG combination, healthcare providers can ensure that canine patients receive optimal sedation and remain stable during surgical procedures. This approach promotes both the well-being of the animal and the success of the procedure.

Dr. Camel's Conclusion

Just like a camel navigating a treacherous desert landscape, veterinarians face challenges in finding the right anesthetic approach for their patients. This study provides a roadmap for achieving safe and effective anesthesia in dogs, ensuring their comfort and well-being throughout the procedure. It is a testament to the dedication and expertise of veterinary professionals in providing compassionate care.

Date :
  1. Date Completed 2022-08-18
  2. Date Revised 2022-08-19
Further Info :

Pubmed ID

35973002

DOI: Digital Object Identifier

ajvr.22.06.0098

Related Literature

SNS
PICO Info
in preparation
Languages

English

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