Diphenhydramine: Time to Move on?

Author: AbramsElissa M, SussmanGordon L, WasermanSusan, WolfsonAnna R, WongDennis

Paper Details 
Original Abstract of the Article :
Diphenhydramine is one of the most widely available, longest-used antihistamine medications but has many side effects including sedation and risk of toxicity in overdose including cardiac toxicity. It is frequently inappropriately used when newer, more favorable antihistamine medications are availab...See full text at original site
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引用元:
https://doi.org/10.1016/j.jaip.2022.07.018

データ提供:米国国立医学図書館(NLM)

Time to Rethink Diphenhydramine: A Shift in Antihistamine Strategies

Diphenhydramine, a widely used antihistamine medication, has long been a mainstay in the treatment of allergies and other conditions. However, its effectiveness comes at a cost, as diphenhydramine can cause significant side effects, including sedation and even cardiac toxicity in overdose. This review explores the potential risks associated with diphenhydramine and advocates for a shift towards newer, more effective antihistamines.

Seeking Safer Alternatives

The authors highlight the availability of newer, second-generation antihistamines that offer similar benefits with fewer side effects. They argue that the widespread availability and affordability of these newer medications make diphenhydramine a less desirable option. The review encourages a reevaluation of antihistamine strategies, emphasizing the need to prioritize patient safety and minimize potential adverse effects.

Navigating the World of Antihistamines

The research provides a compelling case for a shift away from diphenhydramine, emphasizing the importance of informed decision-making in choosing medications. It underscores the need for healthcare providers to stay abreast of the latest evidence and advocate for the use of safer and more effective treatment options.

Dr.Camel's Conclusion

Diphenhydramine, like a mirage in the desert, can appear appealing but can lead to unintended consequences. This review, like a clear compass, guides us toward safer and more effective antihistamines. It's a reminder that the landscape of medicine is constantly evolving, and it's crucial to stay informed and make informed choices for our health. Remember, just as a wise desert traveler chooses the right path to avoid hidden dangers, we must carefully select medications to ensure our well-being.

Date :
  1. Date Completed 2022-12-16
  2. Date Revised 2022-12-22
Further Info :

Pubmed ID

35999169

DOI: Digital Object Identifier

10.1016/j.jaip.2022.07.018

SNS
PICO Info
in preparation
Languages

English

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