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The effects of reserpine on depression: A systematic review.

Author: CaveJeremy, JauharSameer, JavedRahila R, StrawbridgeRebecca, YoungAllan H

Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Reserpine, an antihypertensive drug, is rarely used due to the assumption that it causes depression. This review examines the conflicting evidence to determine if there is a link between reserpine and depression.
Paper Details　
Original Abstract of the Article :
Reserpine is an effective antihypertensive drug, but its role in routine practice has declined such that it is rarely used. This is largely based on the assumption that reserpine causes depression. This assumption was a foundation for the original monoamine hypothesis of depression. However, there r...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10076328/

データ提供：米国国立医学図書館（NLM）

Reserpine and Depression: A Desert of Controversy

The relationship between reserpine, an antihypertensive drug, and depression has been a topic of debate for decades, like a desert landscape shrouded in mystery. This research systematically reviews the evidence to shed light on this complex issue. The authors, like intrepid desert explorers, navigate through a vast body of literature, examining the historical context, conflicting findings, and potential mechanisms underlying the association between reserpine and depression. Their review provides a comprehensive overview of the current understanding of this controversial topic.

Unraveling the Mystery of Reserpine and Depression

This research provides a valuable roadmap through the complex landscape of reserpine and depression. The authors meticulously analyze the evidence, offering a nuanced perspective on this long-standing debate. Their findings provide a solid foundation for future research and clinical decision-making.

Navigating the Desert of Uncertainty

The relationship between reserpine and depression remains a topic of ongoing investigation. This research, like a compass guiding desert travelers, helps to navigate the complex and sometimes contradictory information surrounding this issue.

Dr.Camel's Conclusion

The question of whether reserpine causes depression is a complex one, akin to a desert puzzle with many pieces. This systematic review offers valuable insights, helping to shed light on this controversial topic. Further research is needed to clarify the relationship between reserpine and depression, ultimately paving the way for safer and more effective treatment options for both hypertension and depression.

Date :
  1. Date Completed 2023-04-04
  2. Date Revised 2023-06-03
Further Info :

Pubmed ID

36000248

DOI: Digital Object Identifier

PMC10076328

Related Literature

Article Analysis
・Effects of reserpine・Effects of reserpine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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