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Armodafinil to reduce the sleepiness related side-effects of sleep restriction therapy being used to treat insomnia disorder: An open label clinical trial pilot study compared with historical controls.

Author: BartlettDelwyn J, EspieColin A, GrunsteinRon R, JomaaIbrahim, JudgeDaniel J, KyleSimon D, MarshallNathaniel S, MillerChristopher B, SainiBandana, SemsarianCaitlin R, WongKeith K W, YeeBrendon J

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Sleep restriction therapy (SRT) is effective for insomnia, but daytime sleepiness can be a problem. This pilot trial explored the potential benefit of adding armodafinil to SRT. While SRT alone was effective, armodafinil did not provide additional benefit and was associated with side effects.
Paper Details　
Original Abstract of the Article :
Sleep restriction therapy (SRT) is an effective stand-alone behavioural intervention for insomnia disorder. However, its daytime side effects, particularly sleepiness, may be troubling for patients and/or may be a necessary part of the patient's treatment journey. This pilot trial aims to explore th...See full text at original site
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引用元：
https://doi.org/10.1111/jsr.13699

データ提供：米国国立医学図書館（NLM）

Armodafinil: A Potential Adjunct to Sleep Restriction Therapy for Insomnia

Dr. Camel knows that a good night's sleep is essential for overall well-being, and this study explores the potential of armodafinil, a wakefulness promoter, to reduce the daytime sleepiness often associated with sleep restriction therapy (SRT) for insomnia disorder. The researchers aimed to evaluate the effectiveness of armodafinil as an adjunct to SRT in improving insomnia symptoms and reducing daytime sleepiness.

Armodafinil's Impact on Insomnia Symptoms

While the study found that SRT alone was effective in reducing insomnia severity, the addition of armodafinil did not provide any significant additional benefits in improving insomnia symptoms or reducing daytime sleepiness. This suggests that armodafinil may not be a suitable adjunct to SRT for insomnia disorder.

Navigating Insomnia Treatment

Individuals struggling with insomnia should consult with a healthcare professional to explore the most appropriate treatment options for their specific needs. Sleep restriction therapy is a well-established behavioral intervention for insomnia, and it may be effective for many individuals. However, it's important to discuss potential side effects and the need for further evaluation to determine the optimal course of treatment.

Dr. Camel's Conclusion

Dr. Camel finds this research insightful as it highlights the importance of carefully evaluating the efficacy of potential adjunctive treatments for insomnia. It's crucial to rely on evidence-based approaches and to tailor treatment strategies to individual needs. While armodafinil may not be a suitable adjunct for SRT, further research may uncover its potential benefits in other contexts. Dr. Camel always encourages individuals to consult with their healthcare providers to make informed decisions regarding their health and treatment.

Date :
  1. Date Completed 2023-01-23
  2. Date Revised 2023-02-02
Further Info :

Pubmed ID

36003019

DOI: Digital Object Identifier

10.1111/jsr.13699

Related Literature

Article Analysis
・Side Effects of armodafinil
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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