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Vitamin D receptor activation is a feasible therapeutic target to impair adrenocortical tumorigenesis.
Author: AntoniniSonir Roberto R, BuenoAna Carolina, LealLeticia Ferro, Marrero-GutiérrezJunier, MontaldiAna Paula, MoreCandy Bellido, RamalhoFernando Silva, VêncioRicardo Zorzetto Nicoliello, de Almeida E SilvaDanillo C, de CastroMargaret
Original Abstract of the Article :
OBJECTIVE: To evaluate the therapeutic potential of vitamin D receptor (VDR) signaling in adrenocortical carcinoma (ACC) cells. METHODS: We evaluated VDR's methylation pattern in H295R ACC cells, and investigated the effects of calcitriol and seocalcitol treatments on adrenocortical tumorigenesis. ...See full text at original site
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引用元:
https://doi.org/10.1016/j.mce.2022.111757
データ提供:米国国立医学図書館(NLM)
Vitamin D: A Potential Weapon Against Adrenocortical Tumors
Adrenocortical carcinoma (ACC), a rare but aggressive form of cancer, affects the adrenal glands, which play a vital role in hormone production. This study explores the therapeutic potential of vitamin D receptor (VDR) activation in treating ACC. The researchers investigated the effects of calcitriol and seocalcitol, two forms of vitamin D, on ACC cells, finding that they significantly inhibited tumor growth and reduced hormone production. Their findings suggest that VDR activation may be a promising therapeutic target for ACC.
Vitamin D: A New Hope for Adrenocortical Cancer
This study presents a promising new avenue for treating ACC. The researchers found that activating the VDR significantly inhibited tumor growth and hormone production in ACC cells. These findings suggest that vitamin D, commonly known for its bone-strengthening properties, may also play a role in fighting cancer. Further research is needed to confirm these findings in humans, but it offers a glimmer of hope for individuals facing this challenging disease.
Maintaining Adrenal Health: A Holistic Approach
The adrenal glands, like hidden oases in the desert of our bodies, play a crucial role in our overall health. This research highlights the potential of vitamin D in managing ACC. While further research is needed, it's a reminder that maintaining overall health, including a balanced diet, regular exercise, and stress management, can contribute to healthy adrenal function and well-being.
Dr.Camel's Conclusion
The journey of cancer treatment can be as vast and challenging as a desert trek. This study offers a ray of hope, highlighting the potential of vitamin D in fighting adrenocortical cancer. It's a reminder that even in the face of adversity, there are oases of scientific discovery waiting to be explored, offering a path toward a healthier future.
Date :
- Date Completed 2022-10-27
- Date Revised 2022-12-13
Further Info :
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