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Drug-drug interactions between direct-acting antivirals and co-medications: a territory-wide cohort study.

Author: AuChristopher Langjun, ChanHenry Lik-Yuen, HuiVicki Wing-Ki, LaiJimmy Che-To, LamAmy Shuk Man, TseYee-Kit, WongGrace Lai-Hung, WongVincent Wai-Sun, YipTerry Cheuk-Fung

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study examines the prevalence and degree of drug-drug interactions (DDIs) between direct-acting antiviral (DAA) regimens for hepatitis C virus (HCV) and other co-medications.
Paper Details　
Original Abstract of the Article :
The increasing number of direct-acting antiviral (DAA) regimens along with limited number of subjects and co-medications involved in clinical trials results in drug-drug interactions (DDIs) with DAAs is to be determined. We aimed to examine the prevalence and degree of DDIs between DAAs and other co...See full text at original site
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引用元：
https://doi.org/10.1007/s12072-022-10402-y

データ提供：米国国立医学図書館（NLM）

Unraveling the Interactions of Antiviral Drugs

The field of infectious disease research is constantly evolving, particularly in the fight against viral infections. This study tackles the complex interplay between direct-acting antiviral (DAA) regimens and other medications, a crucial aspect of patient care. With the increasing availability of DAAs, the researchers aimed to investigate the potential for drug-drug interactions (DDIs) in a territory-wide cohort of individuals living with chronic hepatitis C virus (HCV). The study meticulously examined the prevalence and severity of DDIs between DAAs and other co-medications, providing valuable insights into the safety and efficacy of these treatments.

Drug Interactions: A Complex Puzzle

The study revealed a considerable prevalence of DDIs involving DAAs. The results demonstrate the importance of careful medication management and the need for healthcare providers to be mindful of potential interactions. This research serves as a valuable resource for clinicians, highlighting the need for a comprehensive understanding of DDI risks in patients receiving DAA therapy.

Navigating the Desert of Drug Interactions

The study's findings emphasize the importance of a vigilant approach to medication management. This research serves as a reminder that the desert of drug interactions is vast and complex, requiring careful consideration of potential risks. Healthcare providers must carefully assess individual patient profiles and prioritize patient safety by minimizing the potential for harmful drug interactions.

Dr. Camel's Conclusion

The study serves as a reminder that the journey through the desert of drug interactions requires constant vigilance. By understanding the potential for DDIs, clinicians can navigate this landscape effectively, ensuring patient safety and optimizing treatment outcomes. The research underscores the importance of careful medication management and ongoing collaboration between healthcare professionals and patients.

Date :
  1. Date Completed 2022-11-29
  2. Date Revised 2022-11-29
Further Info :

Pubmed ID

36074319

DOI: Digital Object Identifier

10.1007/s12072-022-10402-y

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Languages

English

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