Paper Details

  1. Home
  2. Paper Details

AGA Clinical Practice Update on the Evaluation and Management of Acute Kidney Injury in Patients With Cirrhosis: Expert Review.

Author: AhnJoseph, FlammSteven L, KamathPatrick S, WongFlorence

ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Practice GuidelineGuidelines and recommendations for the diagnosis and treatment of specific medical conditions in medical practice.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This AGA Institute Clinical Practice Update provides recommendations for managing patients with suspected acute kidney injury (AKI) in those with cirrhosis. AKI is diagnosed based on serum creatinine and urine output criteria. Preventive measures include avoiding nephrotoxic medications, diuretics, and large-volume paracentesis without albumin replacement. Treatment includes fluid replacement, albumin administration, and addressing the underlying cause. For hepatorenal syndrome with AKI (HRS-AKI), albumin, vasoactive agents like terlipressin, octreotide, midodrine, or norepinephrine are recommended. Liver transplantation is the most effective treatment for HRS-AKI.
Paper Details　
Original Abstract of the Article :
DESCRIPTION: The purpose of this American Gastroenterological Association (AGA) Institute Clinical Practice Update is to review the available published evidence and expert advice regarding the clinical management of patients with suspected acute kidney injury in patients with cirrhosis. METHODS: Th...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1016/j.cgh.2022.08.033

データ提供：米国国立医学図書館（NLM）

Navigating the Desert of Acute Kidney Injury in Cirrhosis

Acute kidney injury (AKI) in cirrhosis is a treacherous journey through a desert of complications. This American Gastroenterological Association (AGA) Institute Clinical Practice Update acts as a compass, guiding clinicians through the diagnosis and management of this challenging condition. This expert review provides practical advice based on the best available evidence, offering a roadmap for navigating this complex landscape.

Understanding the Landscape

The authors emphasize the importance of early diagnosis and prevention. They recommend a multi-pronged approach, including avoiding nephrotoxic medications, managing diuretics and beta-blockers, and advising patients to avoid alcohol. The update also provides a comprehensive overview of different types of AKI in cirrhosis, helping clinicians identify the specific cause for effective treatment.

Hydration is Key

Staying hydrated is critical in this desert. The update stresses the importance of fluid replacement, including the use of albumin, and closely monitoring fluid status to prevent complications such as pulmonary edema. The authors also discuss the role of renal replacement therapy (RRT) and liver transplantation, emphasizing that these interventions should be tailored to the individual patient's needs.

Dr. Camel's Conclusion

AKI in cirrhosis is like traversing a vast and unforgiving desert. This expert review provides a vital roadmap for clinicians, equipping them with the knowledge to navigate this complex terrain. Early diagnosis, prevention, and tailored management are key to improving outcomes for patients with AKI in cirrhosis. Remember, just as a camel adapts to survive in the desert, healthcare professionals must adapt and evolve their treatment strategies to address the unique challenges of this condition.

Date :
  1. Date Completed 2022-11-28
  2. Date Revised 2023-01-25
Further Info :

Pubmed ID

36075500

DOI: Digital Object Identifier

10.1016/j.cgh.2022.08.033

Related Literature

Article Analysis
・Side Effects of octreotide
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.