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Rimegepant, Ubrogepant, and Lasmiditan in the Acute Treatment of Migraine Examining the Benefit-Risk Profile Using Number Needed to Treat/Harm.
Author: CoricVladimir, CroopRobert, HarrisLinda, JohnstonKarissa M, L'ItalienGilbert, PopoffEvan, PowellLauren
Original Abstract of the Article :
OBJECTIVES: To develop and compare benefit-risk profiles for rimegepant, ubrogepant, and lasmiditan based on a network meta-analysis (NMA) of published clinical trials. METHODS: A fixed-effects Bayesian NMA of randomized controlled trials of lasmiditan, rimegepant, and ubrogepant for the acute trea...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9555761/
データ提供:米国国立医学図書館(NLM)
Comparing Migraine Treatments: A Desert of Choices
In the vast and often uncomfortable world of [migraine], finding effective and safe treatments can feel like searching for a reliable source of relief in a desert. This study, like a skilled desert guide, compares the benefit-risk profiles of three migraine treatments: rimegepant, ubrogepant, and lasmiditan. The researchers, like explorers charting a new course, used a network meta-analysis to compare the efficacy and safety of these treatments, seeking to provide a more comprehensive understanding of their relative benefits and risks.
The study, like a well-stocked caravan, provides valuable insights into the efficacy and safety profiles of these migraine medications. The researchers found that rimegepant and ubrogepant, like a refreshing oasis in a parched desert, were associated with the highest rates of pain relief and pain freedom, while lasmiditan, despite offering some benefits, was associated with a higher risk of adverse effects, a potential pitfall on the journey to relief.
Navigating the Desert of Migraine Treatment Options
This study, like a compass guiding us through the complex landscape of migraine treatment, provides valuable information that can help patients and their doctors make informed decisions. The findings suggest that rimegepant and ubrogepant, like reliable sources of water in the desert, could offer the most effective and safest treatment options for many patients.
Migraine Treatment: A Desert of Considerations
Navigating the desert of migraine treatment options requires careful consideration of the individual patient's needs, the potential risks and benefits of each treatment, and the guidance of a trusted healthcare provider. This study, like a well-prepared caravan, provides valuable insights that can inform decision-making and optimize treatment outcomes.
Dr.Camel's Conclusion
This study, like a camel caravan traversing a vast desert landscape, reminds us that the search for effective migraine treatments continues. The researchers' findings offer valuable insights into the relative benefits and risks of different migraine medications, providing patients and their doctors with a more comprehensive understanding of the options available. As always, the journey to optimal health requires careful consideration of individual needs and the guidance of a trusted healthcare provider.
Date :
- Date Completed 2022-10-13
- Date Revised 2023-08-27
Further Info :
Related Literature
English
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