Rimegepant, Ubrogepant, and Lasmiditan in the Acute Treatment of Migraine Examining the Benefit-Risk Profile Using Number Needed to Treat/Harm.

Author: CoricVladimir, CroopRobert, HarrisLinda, JohnstonKarissa M, L'ItalienGilbert, PopoffEvan, PowellLauren

Paper Details 
Original Abstract of the Article :
OBJECTIVES: To develop and compare benefit-risk profiles for rimegepant, ubrogepant, and lasmiditan based on a network meta-analysis (NMA) of published clinical trials. METHODS: A fixed-effects Bayesian NMA of randomized controlled trials of lasmiditan, rimegepant, and ubrogepant for the acute trea...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9555761/

データ提供:米国国立医学図書館(NLM)

Comparing Migraine Treatments: A Desert of Choices

In the vast and often uncomfortable world of [migraine], finding effective and safe treatments can feel like searching for a reliable source of relief in a desert. This study, like a skilled desert guide, compares the benefit-risk profiles of three migraine treatments: rimegepant, ubrogepant, and lasmiditan. The researchers, like explorers charting a new course, used a network meta-analysis to compare the efficacy and safety of these treatments, seeking to provide a more comprehensive understanding of their relative benefits and risks.

The study, like a well-stocked caravan, provides valuable insights into the efficacy and safety profiles of these migraine medications. The researchers found that rimegepant and ubrogepant, like a refreshing oasis in a parched desert, were associated with the highest rates of pain relief and pain freedom, while lasmiditan, despite offering some benefits, was associated with a higher risk of adverse effects, a potential pitfall on the journey to relief.

Navigating the Desert of Migraine Treatment Options

This study, like a compass guiding us through the complex landscape of migraine treatment, provides valuable information that can help patients and their doctors make informed decisions. The findings suggest that rimegepant and ubrogepant, like reliable sources of water in the desert, could offer the most effective and safest treatment options for many patients.

Migraine Treatment: A Desert of Considerations

Navigating the desert of migraine treatment options requires careful consideration of the individual patient's needs, the potential risks and benefits of each treatment, and the guidance of a trusted healthcare provider. This study, like a well-prepared caravan, provides valuable insights that can inform decision-making and optimize treatment outcomes.

Dr.Camel's Conclusion

This study, like a camel caravan traversing a vast desert landscape, reminds us that the search for effective migraine treatments continues. The researchers' findings offer valuable insights into the relative benefits and risks of different migraine medications, providing patients and their doctors with a more comprehensive understanding of the options available. As always, the journey to optimal health requires careful consideration of individual needs and the guidance of a trusted healthcare provider.

Date :
  1. Date Completed 2022-10-13
  2. Date Revised 2023-08-27
Further Info :

Pubmed ID

36125279

DOI: Digital Object Identifier

PMC9555761

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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