Paper Details 
Original Abstract of the Article :
Calcitonin gene-related peptide (CGRP) is involved in several of the pathophysiological processes underpinning migraine attacks. Therapies that target CGRP or its receptor have shown efficacy as preventive or acute treatments for migraine. Two small-molecule CGRP receptor antagonists (rimegepant and...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9651456/

データ提供:米国国立医学図書館(NLM)

CGRP and Migraine: A Desert Storm

The world of migraine is complex and challenging, like a desert storm, with sudden bouts of intense pain. This study delves into the role of calcitonin gene-related peptide (CGRP) in migraine, exploring its impact on gastrointestinal symptoms. The authors sought to understand the relationship between CGRP, migraine, and gastrointestinal disorders, offering insights into potential treatment strategies.

Uncovering the Hidden Oasis: CGRP's Role

Like a skilled desert explorer, this research revealed the significant role of CGRP in various aspects of migraine, including gastrointestinal symptoms. CGRP's involvement in gastrointestinal nociception, inflammation, gastric acid secretion, and motility suggests its potential contribution to the nausea and vomiting commonly associated with migraine. The study highlights the need for further research to fully understand the complex interplay between CGRP and migraine, especially in relation to gastrointestinal disorders.

Navigating the Desert: A Camel's Advice

Navigating the desert of migraine can be challenging, and understanding the role of CGRP is crucial for managing the condition. It's important to talk to your doctor about any gastrointestinal symptoms you experience, as they may be related to migraine. Just as a camel relies on its instincts in the desert, it's important to listen to your body and seek professional guidance to manage your migraine effectively.

Dr.Camel's Conclusion

This study provides a valuable overview of CGRP's role in migraine, particularly its potential connection to gastrointestinal symptoms. It underscores the importance of considering this peptide when developing and implementing treatment strategies for migraine. Like a camel navigating a desert storm, it's essential to understand the factors contributing to migraine and seek effective solutions to manage this challenging condition.

Date :
  1. Date Completed n.d.
  2. Date Revised 2023-02-07
Further Info :

Pubmed ID

36127137

DOI: Digital Object Identifier

PMC9651456

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Languages

English

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