Paper Details

  1. Home
  2. Paper Details

Breastfeeding while on treatment with antiseizure medications: a systematic review from the ILAE Women Task Force

Author: BattinoDina, BromleyRebecca, KochenSilvia, MeadorKimford J., PennellPage B., ThomasSanjeev V., TomsonTorbjörn

Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study investigates the safety of breastfeeding for mothers on antiseizure medications (ASMs). The authors found that for most ASMs, breastfed infants receive very low concentrations of the drug (10% or less of maternal levels). However, high levels of ASMs (30% to 100% of maternal levels) were reported for ethosuximide, phenobarbital and zonisamide. While adverse infant effects were rare, more long-term follow-up studies are needed to assess developmental outcomes. Overall, breastfeeding is generally encouraged for mothers on ASMs due to its health benefits for infants.
Paper Details　
Original Abstract of the Article :
We carried out a systematic review of published information on transfer of antiseizure medications (ASMs) into breastmilk, ASM serum concentrations in breastfed infants, and the wellbeing of infants breastfed by mothers on ASM treatment. Information was extracted from 85 relevant articles. No data o...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1684/epd.2022.1492

データ提供：米国国立医学図書館（NLM）

Breastfeeding While on Antiseizure Medications: Navigating the Desert of Motherhood

This study investigates the impact of antiseizure medications (ASMs) on breastfeeding, exploring the transfer of ASMs into breast milk, ASM serum concentrations in breastfed infants, and the well-being of infants breastfed by mothers on ASM treatment. It's like a camel caravan traversing the desert of motherhood, seeking to understand the complexities of breastfeeding while managing epilepsy. The researchers conducted a systematic review of published information on ASMs and breastfeeding, examining the available data on ASM levels in breast milk and infants. Their findings suggest that breastfeeding is generally encouraged for women taking ASMs, as the benefits of breastfeeding outweigh the potential risks associated with ASM exposure.

The Oasis of Breastfeeding: Benefits Outweigh Risks

The study provides reassuring evidence that breastfeeding is generally safe for mothers taking ASMs. The researchers found that ASM levels in breastfed infants are typically very low, with no significant adverse effects reported.

Navigating the Desert of Epilepsy and Motherhood: A Journey of Support

This study underscores the importance of personalized counseling and support for mothers with epilepsy who wish to breastfeed. It emphasizes the need for individualized information and guidance, considering the specific ASM regimen and the individual patient's circumstances.

Dr. Camel's Conclusion

This study offers a beacon of hope for mothers with epilepsy who wish to breastfeed. It provides evidence that breastfeeding is generally safe and beneficial for both mothers and infants, even with ASM treatment. It's a testament to the power of informed decision-making and supportive care in navigating the desert of epilepsy and motherhood.
Date :
  1. Date Completed 2022-10-05
  2. Date Revised 2022-12-12
Further Info :

Pubmed ID

36193017

DOI: Digital Object Identifier

10.1684/epd.2022.1492

Related Literature

Article Analysis
・Effects of stiripentol・Effects of rufinamide
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.