Novel Drug Design for Treatment of COVID-19: A Systematic Review of Preclinical Studies.

Author: FeiziAwat, MirzaeiMahmoud, MousaviSarah, ZareShima

Paper Details 
Original Abstract of the Article :
Since the beginning of the novel coronavirus (SARS-CoV-2) disease outbreak, there has been an increasing interest in discovering potential therapeutic agents for this disease. In this regard, we conducted a systematic review through an overview of drug development (in silico, in vitro, and in vivo) ...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9527439/

データ提供:米国国立医学図書館(NLM)

A New Frontier in COVID-19 Treatment: A Systematic Review of Preclinical Drug Design

The COVID-19 pandemic has been a relentless storm, sweeping across the globe and leaving a trail of devastation. This research, like a tireless desert explorer searching for a solution to a drought, focuses on the urgent need for new and effective treatments for this disease. The authors conducted a systematic review of preclinical studies, examining the vast landscape of potential therapeutic agents. They used a rigorous approach, like a seasoned explorer using a compass and map, to navigate the complex terrain of drug discovery.

The review examines a range of drug development strategies, including in silico (computer-based), in vitro (cell-based), and in vivo (animal-based) studies. This multi-faceted approach, like a caravan exploring different routes through the desert, allows the researchers to comprehensively assess the potential of various drugs and therapies. The authors highlight promising candidates that have shown efficacy in preclinical settings, offering a ray of hope in the fight against COVID-19.

A Beacon of Hope in the COVID-19 Desert

This research provides a valuable roadmap for the development of new COVID-19 treatments. The systematic review, like a carefully constructed oasis, offers a place for researchers to gather, share their findings, and collaborate on finding solutions. The study's findings highlight the potential of various drugs and therapies, giving us reason to believe that effective treatments for COVID-19 are within reach.

Navigating the Challenges of Pandemic Research

As a researcher, I am deeply impressed by the comprehensive and systematic approach taken in this review. It highlights the critical role of preclinical research in the fight against COVID-19. We must continue to explore the desert of medical possibilities, seeking to develop new and effective treatments to protect ourselves and our communities. This research serves as a valuable guide, illuminating the path towards a brighter future, free from the shadow of this pandemic.

Dr.Camel's Conclusion

This systematic review provides a valuable overview of preclinical drug development efforts for COVID-19, highlighting promising candidates and strategies for combatting this devastating pandemic. It's like a beacon of hope shining brightly in the desert, guiding us towards a brighter and healthier future.

Date :
  1. Date Completed n.d.
  2. Date Revised 2022-10-07
Further Info :

Pubmed ID

36199815

DOI: Digital Object Identifier

PMC9527439

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Languages

English

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