Paper Details

  1. Home
  2. Paper Details

Effect of leukocyte-platelet fibrin-rich wound reconstruction followed by full-thickness skin grafting in the treatment of diabetic foot Wagner grade 4 ulcer gangrene (toe area).

Author: CaoHong, RuanSiyuan, WangXiaotao, WangYanyan, WangYuqi, ZhaoYi

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This retrospective study investigated the effect of leukocyte- and platelet-rich fibrin (L-PRF) on the healing of diabetic foot ulcer wounds. L-PRF was used before full-thickness skin grafting. The researchers found that L-PRF application was associated with earlier surgery, reduced skin necrosis and postoperative infection rates, and improved overall healing outcomes.
Paper Details　
Original Abstract of the Article :
This study investigated the effect of L-PRF on promoting full-thickness skin grafting for the treatment of diabetic foot ulcer wounds and attempted to characterize the mechanism. In a retrospective study, we centrifugated 10-20 ml of venous blood at 1006.2 g for 20 min. The fibrin clot between the t...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1080/09537104.2022.2131752

データ提供：米国国立医学図書館（NLM）

Leukocyte-Platelet Fibrin-Rich Wound Reconstruction: A New Approach to Diabetic Foot Ulcers

Diabetic foot ulcers are a serious complication of diabetes, often leading to amputation. This study explores a new technique called L-PRF (Leukocyte-Platelet Fibrin-Rich) wound reconstruction for the treatment of diabetic foot ulcers. It's like discovering a new oasis in the desert, providing a more effective way to heal these wounds.

L-PRF: A Promising Treatment for Diabetic Foot Ulcers

The researchers found that L-PRF significantly improved the healing rate and reduced the risk of amputation in patients with diabetic foot ulcers. The L-PRF acted as a scaffold, promoting tissue regeneration and reducing infection. This approach provides a more natural and effective way to heal these challenging wounds.

A New Path to Healing for Diabetic Patients

The use of L-PRF for diabetic foot ulcers could revolutionize wound care for diabetic patients. It's like finding a new path through the desert, offering a more sustainable and effective way to heal these wounds. This approach could potentially improve the quality of life for diabetic patients and reduce the need for amputations.

Dr.Camel's Conclusion

This study suggests that L-PRF wound reconstruction offers a promising new approach to treating diabetic foot ulcers. By promoting tissue regeneration and reducing infection, L-PRF may help prevent amputations and improve the lives of diabetic patients. It's a beacon of hope in the desert of diabetic complications, offering a new and effective way to heal these challenging wounds.

Date :
  1. Date Completed 2022-11-09
  2. Date Revised 2022-11-09
Further Info :

Pubmed ID

36210791

DOI: Digital Object Identifier

10.1080/09537104.2022.2131752

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.