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Pyridoxine for treatment of levetiracetam-induced behavioral adverse events: A randomized double-blind placebo-controlled trial.

Author: Alizadeh-NavaeiReza, AsghariFaezeh, CheraghmakaniHamed, GhazaeianMonireh, RezapourMaryam, TabriziNasim

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This clinical trial evaluated the effect of pyridoxine on behavioral side effects of levetiracetam in adult patients with epilepsy.
Paper Details　
Original Abstract of the Article :
Levetiracetam is a broad-spectrum antiseizure medication with known behavioral side effects. The possible beneficial effect of pyridoxine on improvement of these psychiatric problems has been suggested in few previous studies. This clinical trial aimed to investigate the effect of pyridoxine on beha...See full text at original site
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引用元：
https://doi.org/10.1016/j.yebeh.2022.108938

データ提供：米国国立医学図書館（NLM）

Tackling the Side Effects of Levetiracetam: A Study on Behavioral Adverse Events

Levetiracetam is a powerful tool in our fight against epilepsy, but like many potent drugs, it can have its drawbacks. This study dives deep into the [behavioral side effects of levetiracetam] in patients with epilepsy. The authors investigate whether [pyridoxine, also known as vitamin B6] can help mitigate these adverse effects. They [conducted a randomized double-blind placebo-controlled trial] to compare the effects of pyridoxine against a placebo. This is like testing different watering strategies in a desert garden – we want to see which one helps our plants thrive. The study [investigated the effect of pyridoxine on behavioral side effects of levetiracetam].

A Ray of Hope for Patients Experiencing Behavioral Side Effects

The findings suggest that pyridoxine may have [a beneficial effect] on [improving behavioral side effects] associated with levetiracetam. While the study needs further investigation, it provides a promising [avenue for exploring alternative treatments] for patients experiencing these adverse effects.

Navigating the Side Effects of Epilepsy Treatment

Patients with epilepsy often face a delicate balance between controlling seizures and managing medication side effects. This research provides [a potential avenue for reducing behavioral side effects]. It's important for patients to [communicate any concerns] about medication side effects with their physicians. This open dialogue allows for more personalized treatment strategies.

Dr.Camel's Conclusion

This study provides a glimmer of hope for patients experiencing behavioral side effects from levetiracetam. It's a testament to the ongoing research and development in the field of epilepsy treatment. With further research, we can hope to find even better solutions for patients and help them navigate the challenging desert of epilepsy treatment.

Date :
  1. Date Completed 2022-11-07
  2. Date Revised 2022-12-13
Further Info :

Pubmed ID

36228485

DOI: Digital Object Identifier

10.1016/j.yebeh.2022.108938

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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