Safety and efficacy of ranolazine in hypertrophic cardiomyopathy: Real-world experience in a National Referral Center.

Author: ArgiròAlessia, BaldiniKatia, CappelliFrancesco, CoppiniRaffaele, DeiLorenzo-Lupo, FavilliSilvia, FerrantiniCecilia, GabrieleMartina, MarchiAlberto, MarchionniNiccolò, MauriziNiccolò, OlivottoIacopo, PassantinoSilvia, TassettiLuigi, TomberliAlessia, ZampieriMattia, ZocchiChiara

Paper Details 
Original Abstract of the Article :
OBJECTIVES: We assessed the efficacy and safety of ranolazine in real-world patients with hypertrophic cardiomyopathy (HCM). BACKGROUND: Ranolazine is an anti-anginal drug that inhibits the late phase of the inward sodium current. In a small prospective trial, ranolazine reduced the arrhythmic burd...See full text at original site
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引用元:
https://doi.org/10.1016/j.ijcard.2022.10.014

データ提供:米国国立医学図書館(NLM)

Ranolazine: A New Path for Hypertrophic Cardiomyopathy Management

The world of cardiology is a vast and intricate desert, where researchers are constantly seeking to understand and treat heart conditions. This study investigates the efficacy and safety of ranolazine, an anti-anginal drug, in managing hypertrophic cardiomyopathy (HCM), a condition that causes the heart muscle to thicken. The researchers, like seasoned desert explorers, are carefully navigating the complexities of heart disease, seeking to improve patient outcomes.

The study found that ranolazine was well-tolerated and effective in relieving angina, a type of chest pain associated with HCM, in a significant number of patients. This is like discovering a hidden oasis in the desert, offering a potential solution for improving the quality of life for patients with HCM. The study also revealed that ranolazine may be beneficial in preventing ventricular arrhythmias, irregular heartbeats that can be life-threatening.

Ranolazine: A New Oasis in the Desert of Cardiology

The study's findings suggest that ranolazine may be a valuable treatment option for patients with HCM and angina. This drug has the potential to improve symptoms, enhance quality of life, and potentially reduce the risk of serious heart rhythm disturbances. The results are like discovering a fresh spring in the desert, bringing new hope and possibilities for patients with this challenging condition.

Navigating Heart Health in the Desert of Cardiology

This research highlights the importance of considering the potential benefits of ranolazine in managing HCM. It is like a camel caravan equipped with a detailed map, guiding clinicians through the complex landscape of cardiovascular health. The findings underscore the need for continued research and vigilance in monitoring the effects of ranolazine on heart health, ensuring that we are always one step ahead of potential complications.

Dr.Camel's Conclusion

This research provides a valuable roadmap through the vast and complex desert of cardiology. The study's findings highlight the potential benefits of ranolazine in managing hypertrophic cardiomyopathy (HCM), offering a potentially more effective treatment option for angina and arrhythmias. It's a reminder that the journey through this desert is ongoing, with continuous research and innovation guiding us towards better strategies for managing heart disease and improving patient outcomes.

Date :
  1. Date Completed 2022-12-16
  2. Date Revised 2022-12-21
Further Info :

Pubmed ID

36228766

DOI: Digital Object Identifier

10.1016/j.ijcard.2022.10.014

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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