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Effects of cenobamate on cognitive performance of epilepsy patients.

Author: AltenmüllerDirk-Matthias, Castillo-RodriguezMaria, HeersMarcel, HirschMartin, KravalisKristina, Martínez-LizanaEva, MetternichBirgitta, PapadopoulouGeorgia, SchuetzElisa, Schulze-BonhageAndreas, WagnerKathrin

Observational StudyResearch that observes and collects data on participants' behavior and outcomes in their natural state, without intervention.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

The effects of cenobamate on cognition are unclear. Further research is needed to determine if adjunctive treatment with cenobamate is associated with changes in cognitive performance.
Paper Details　
Original Abstract of the Article :
Cenobamate (CNB) is a new antiseizure medication (ASM) for the treatment of focal epilepsy in adults. While efficacy of CNB was confirmed in controlled clinical trials, its effects on cognition are unclear. Cognitive adverse effects of ASM affect quality of life and retention rate. Therefore, we inv...See full text at original site
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引用元：
https://doi.org/10.1016/j.seizure.2022.10.004

データ提供：米国国立医学図書館（NLM）

Cenobamate: A New Antiseizure Medication and its Impact on Cognition

Cenobamate (CNB) is a newly introduced antiseizure medication (ASM) for treating focal epilepsy in adults. This research explores the potential impact of CNB on cognitive performance in epilepsy patients. The authors investigated whether adjunctive treatment with CNB is associated with changes in cognitive performance. The study, while acknowledging the need for further research, suggests that the cognitive effects of CNB require careful consideration. The authors emphasize that cognitive adverse effects of ASMs can significantly impact quality of life and treatment adherence.

Cenobamate: Navigating the Balance Between Seizure Control and Cognitive Function

This study highlights the importance of carefully evaluating the cognitive impact of new antiseizure medications. The authors underscore the delicate balance between achieving effective seizure control and maintaining optimal cognitive function. Further research is needed to fully understand the long-term cognitive effects of CNB and to determine effective strategies for managing any potential cognitive side effects.

Open Communication and Monitoring for Epilepsy Patients

For individuals with epilepsy, open communication with their healthcare providers is crucial. If you are taking an ASM, discussing any concerns about cognitive function is essential. Regular cognitive assessments and monitoring can help identify any potential changes and guide appropriate management strategies.

Dr. Camel's Conclusion

Just as a camel navigates the ever-shifting desert landscape, epilepsy patients and their healthcare providers must navigate the complexities of antiseizure medication. This research emphasizes the importance of understanding the cognitive effects of new medications like CNB. It’s a reminder that even seemingly successful treatments can have unintended consequences, highlighting the need for ongoing communication and careful monitoring.

Date :
  1. Date Completed 2022-11-07
  2. Date Revised 2022-11-07
Further Info :

Pubmed ID

36240699

DOI: Digital Object Identifier

10.1016/j.seizure.2022.10.004

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・Side Effects of cenobamate
SNS
PICO Info
in preparation
Languages

English

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