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Comparison potassium sodium hydrogen citrate with sodium bicarbonate in urine alkalization: a prospective crossover-controlled trial.

Author: ChengJiafen, LiuXinying, PengAi, WangLing, XueWen, ZhaoJing

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study compared the effectiveness of sodium bicarbonate (NaHCO3) and potassium sodium hydrogen citrate (PSHC) for urinary alkalization in healthy Chinese participants. Both medications effectively increased urine pH, but PSHC had a less significant impact on the circadian rhythm of urine pH.
Paper Details　
Original Abstract of the Article :
Label="PURPOSE" NlmCategory="OBJECTIVE">Excessive alkalization will increase the incidence of nephrolithiasis. Sodium bicarbonate (NaHCO<sub>3</sub>) and potassium sodium hydrogen citrate (PSHC) are commonly used drugs for urinary alkalization. We designed a trial to compare PSHC with NaHCO<sub>3</s...See full text at original site
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引用元：
https://doi.org/10.1007/s11255-022-03387-y

データ提供：米国国立医学図書館（NLM）

Comparison Potassium Sodium Hydrogen Citrate with Sodium Bicarbonate in Urine Alkalization: A Prospective Crossover-Controlled Trial

This research, like a careful chemist testing different compounds, compares the effectiveness of two drugs, potassium sodium hydrogen citrate (PSHC) and sodium bicarbonate (NaHCO3), in alkalizing urine. The study explores the effects of these drugs on urine pH levels, evaluating their efficacy and impact on circadian rhythms. The study's findings may provide valuable insights into the optimal choice of medication for urinary alkalization, ensuring effective treatment while minimizing potential side effects.

Finding the Right Balance: Comparing Drugs for Urine Alkalization

This research, like a desert explorer seeking the perfect oasis, compares the effectiveness of two drugs, potassium sodium hydrogen citrate (PSHC) and sodium bicarbonate (NaHCO3), in alkalizing urine. The study explores the effects of these drugs on urine pH levels, evaluating their efficacy and impact on circadian rhythms. The findings may provide valuable insights into the optimal choice of medication for urinary alkalization, ensuring effective treatment while minimizing potential side effects.

A Delicate Balance: Maintaining Healthy Urine pH Levels

This research, like a wise camel navigating the desert, highlights the importance of maintaining a healthy urine pH level for overall health. The study explores the effectiveness of two drugs, potassium sodium hydrogen citrate (PSHC) and sodium bicarbonate (NaHCO3), in alkalizing urine. The findings may provide valuable insights into the optimal choice of medication for urinary alkalization, ensuring effective treatment while minimizing potential side effects. This research serves as a reminder of the importance of understanding the complexities of the body's internal environment and the role of pH balance in maintaining overall health.

Dr. Camel's Conclusion

This research, like a camel navigating the vast desert of medical knowledge, compares the effectiveness of two drugs, potassium sodium hydrogen citrate (PSHC) and sodium bicarbonate (NaHCO3), in alkalizing urine. The study explores the effects of these drugs on urine pH levels, evaluating their efficacy and impact on circadian rhythms. The findings may provide valuable insights into the optimal choice of medication for urinary alkalization, ensuring effective treatment while minimizing potential side effects.
Date :
  1. Date Completed 2023-01-04
  2. Date Revised 2023-01-11
Further Info :

Pubmed ID

36261757

DOI: Digital Object Identifier

10.1007/s11255-022-03387-y

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in preparation
Languages

English

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