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Evaluation of first-generation sulfonylureas and glipizide in non-insulin-dependent diabetes mellitus.

Author: BeckmanF, BeisswengerP J, DiasN

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Glipizide, a second-generation sulfonylurea, was more effective at controlling blood sugar in patients with diabetes who had poor control on first-generation sulfonylureas. Glipizide was well-tolerated and had no significant side effects.
Paper Details　
Original Abstract of the Article :
The current study examines the impact of glipizide, a second-generation sulfonylurea, on diabetes control in patients in whom adequate control was not achieved while receiving treatment with first-generation agents. The interim results of this multicenter study are presented in which patients in who...See full text at original site
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引用元：
https://doi.org/10.1016/0002-9343(87)90799-6

データ提供：米国国立医学図書館（NLM）

A New Generation of Sulfonylureas: A Potential Breakthrough for Diabetes Management

Diabetes is a complex metabolic disorder that affects millions worldwide. Imagine the body as a vast desert landscape, where glucose, the body's fuel, is transported through a network of oases. In diabetes, these oases become depleted, leading to a shortage of fuel. Sulfonylureas, a class of drugs, work by stimulating the body's production of insulin, which acts like a desert rain, replenishing the oases. This study compares the effectiveness of first-generation sulfonylureas with glipizide, a newer and more potent drug, in patients with non-insulin-dependent diabetes mellitus (NIDDM). The study found that glipizide was significantly more effective in achieving better blood sugar control compared to older sulfonylureas.

Glipizide: A More Powerful Oasis in Diabetes Management

This study demonstrates the potential of glipizide to significantly improve blood sugar control in patients with NIDDM. The findings suggest that glipizide offers a more effective approach to diabetes management, potentially leading to better long-term outcomes. It's like discovering a new, more powerful oasis in the desert of diabetes management, providing more effective and sustainable relief.

Navigating the Sands of Diabetes Management

The study sheds light on the potential benefits of glipizide for individuals with NIDDM. This research encourages further exploration of newer generation sulfonylureas in diabetes management. It's like finding a new path through the desert of diabetes management, offering a more effective and sustainable approach to combating the disease.

Dr. Camel's Conclusion

This research is a testament to the advancements in diabetes management. The study reveals the potential of glipizide to provide more effective and sustainable blood sugar control for patients with NIDDM. It's like discovering a new and more potent oasis in the desert of diabetes, offering hope for a brighter future for those living with the disease.

Date :
  1. Date Completed 1987-10-22
  2. Date Revised 2022-12-07
Further Info :

Pubmed ID

3631118

DOI: Digital Object Identifier

10.1016/0002-9343(87)90799-6

Related Literature

Article Analysis
・Side Effects of glipizide
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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