In vitro effects of eslicarbazepine (S-licarbazepine) as a potential precision therapy on SCN8A variants causing neuropsychiatric disorders.

Author: BayraktarErva, EltokhiAhmed, HedrichUlrike B S, LauxmannStephan, LercheHolger, LiuYuanyuan, LyuHang, SaraYildirim, SonnenbergLukas, WuttkeThomas V

Paper Details 
Original Abstract of the Article :
Label="BACKGROUND AND PURPOSE">Variants in SCN8A, the Na<sub>V</sub> 1.6 channel's coding gene, are characterized by a variety of symptoms, including intractable epileptic seizures, psychomotor delay, progressive cognitive decline, autistic features, ataxia or dystonia. Standard anticonvulsant treat...See full text at original site
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引用元:
https://doi.org/10.1111/bph.15981

データ提供:米国国立医学図書館(NLM)

Eslicarbazepine: A Potential Precision Therapy for SCN8A-Related Neuropsychiatric Disorders

The world of [neuropsychiatric disorders] is a complex landscape, and [SCN8A] mutations present a unique challenge. This research explores the potential of [eslicarbazepine (S-licarbazepine)] as a precision therapy for these disorders.

The researchers conducted [in vitro] studies to evaluate the effects of eslicarbazepine on cells with SCN8A mutations. They discovered that eslicarbazepine exhibited promising therapeutic effects, suggesting its potential to be a precision therapy for these disorders.

This research is like finding a hidden oasis in the desert of SCN8A-related disorders, offering a potential source of relief for those affected.

A New Oasis in the Desert of SCN8A Disorders

The study suggests that eslicarbazepine could be a promising treatment option for SCN8A-related neuropsychiatric disorders.

It's like finding a new path through the desert, offering hope for patients who have limited treatment options. This research could lead to better outcomes for those struggling with these complex conditions.

Health Impact: A Journey Towards Personalized Treatment

The study highlights the importance of exploring personalized medicine approaches for neuropsychiatric disorders.

It's like a caravan setting out on a long journey, searching for a personalized solution for each traveler. By developing precision therapies like eslicarbazepine, we can create a more tailored approach to healthcare for those with SCN8A-related disorders.

Dr. Camel's Conclusion

The research on eslicarbazepine is a vital step in the ongoing quest for effective treatment for SCN8A-related neuropsychiatric disorders. It's like discovering a hidden spring in the desert that provides clean and safe water for all. With continued research and development, we can create a brighter future for those affected by these complex conditions.

Date :
  1. Date Completed 2023-03-14
  2. Date Revised 2023-04-15
Further Info :

Pubmed ID

36321697

DOI: Digital Object Identifier

10.1111/bph.15981

Related Literature

SNS
PICO Info
in preparation
Languages

English

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