Hypophosphataemia following ferric derisomaltose and ferric carboxymaltose in patients with iron deficiency anaemia due to inflammatory bowel disease (PHOSPHARE-IBD): a randomised clinical trial.

Author: BlumensteinIrina, IqbalTariq, LindgrenStefan, PrimasChristian, ReinischWalter, ThomsenLars L, WolfMyles, ZollerHeinz

Paper Details 
Original Abstract of the Article :
OBJECTIVE: Intravenous iron-a common treatment for anaemia and iron deficiency due to inflammatory bowel disease (IBD)-can cause hypophosphataemia. This trial compared the incidence of hypophosphataemia after treatment with ferric carboxymaltose (FCM) or ferric derisomaltose (FDI). DESIGN: This ran...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086283/

データ提供:米国国立医学図書館(NLM)

Iron Deficiency Anemia: Navigating the Risks of Hypophosphatemia

Iron deficiency anemia is a common condition that can leave individuals feeling weak and tired, like a camel struggling through a desert sandstorm. Intravenous iron infusions are often used to treat this condition, but these treatments can sometimes lead to hypophosphatemia, a condition where the blood phosphate level drops below normal. This research, like a physician carefully monitoring a patient's health, investigated the incidence of hypophosphatemia following intravenous iron infusions using different iron formulations. The researchers found that ferric carboxymaltose (FCM) was associated with a significantly higher rate of hypophosphatemia compared to ferric derisomaltose (FDI).

Iron Therapy: A Balancing Act for Phosphate Levels

This research, like a camel caravan carefully managing its water supply, underscores the importance of monitoring phosphate levels during iron therapy. The study found that FCM led to a significantly higher incidence of hypophosphatemia compared to FDI, highlighting the need for careful consideration of iron formulation choices and regular phosphate monitoring. This information is valuable for healthcare providers seeking to optimize iron therapy while minimizing potential side effects.

Preventing Hypophosphatemia: A Crucial Step in Iron Therapy

This research, like a desert explorer discovering a hidden oasis, emphasizes the importance of preventive measures to mitigate hypophosphatemia during iron therapy. The study's findings suggest that careful selection of iron formulations and regular phosphate monitoring can help reduce the risk of hypophosphatemia. Further research is needed to fully understand the underlying mechanisms behind hypophosphatemia and to develop more targeted strategies for prevention and management.

Dr.Camel's Conclusion

Iron deficiency anemia, like a desert traveler facing a lack of resources, requires careful attention to ensure optimal treatment. This research, like a desert guide offering essential guidance, highlights the importance of considering the potential for hypophosphatemia during iron therapy. By carefully selecting iron formulations and monitoring phosphate levels, healthcare providers can help minimize the risk of hypophosphatemia and ensure the safety and effectiveness of iron treatment.

Date :
  1. Date Completed 2023-03-09
  2. Date Revised 2023-04-13
Further Info :

Pubmed ID

36343979

DOI: Digital Object Identifier

PMC10086283

Related Literature

SNS
PICO Info
in preparation
Languages

English

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