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Proteome-Based Investigation Identified Potential Drug Repurposable Small Molecules Against Monkeypox Disease.
Author: AhammadIshtiaque, BhattacharjeeArittra, ChowdhuryZeshan Mahmud, DasKeshob Chandra, KeyaChaman Ara, SalimullahMd
Original Abstract of the Article :
Monkeypox Virus (MPXV), the causative agent of Monkeypox (MPX) disease, is an emerging zoonotic pathogen spreading in different endemic and non-endemic nations and creating outbreaks. MPX treatment mainly includes Cidofovir and Tecovirimat but they have several side effects and solely depending on t...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648865/
データ提供:米国国立医学図書館(NLM)
Fighting Monkeypox: Finding New Weapons in the Desert of Viral Outbreaks
The emergence of new viral outbreaks is a constant threat, demanding a vigilant and innovative approach to treatment. This study explores the potential for drug repurposing in combating Monkeypox Virus (MPXV), the causative agent of Monkeypox disease. The researchers investigated the MPXV proteome to identify potential targets for repurposed drugs, focusing on the L2R and I4L receptors. They found that several existing drugs, including Zidovudine, Fludarabine, and Harmala alkaloids, showed promising binding affinities to these receptors. This research is like discovering a hidden arsenal of weapons in the desert of viral outbreaks, offering potential new strategies for combating this emerging threat.
Drug Repurposing: A New Arsenal in the Fight Against Monkeypox
The study identified several existing drugs, including Zidovudine, Fludarabine, and Harmala alkaloids, as potential repurposable candidates against Monkeypox Virus (MPXV). This is a significant finding, as it offers a faster and more cost-effective approach to developing new treatments for this emerging viral disease. It's like finding a hidden cache of weapons in the desert of viral outbreaks, providing a potential arsenal for combating this threat.
Navigating the Desert of Viral Outbreaks
This research highlights the potential of drug repurposing as a valuable strategy in combating emerging viral outbreaks. It's a reminder that the desert of viral outbreaks is a challenging landscape, and we must explore all available options to protect public health. This study encourages us to continue seeking out new and innovative approaches to combat emerging infectious diseases, ensuring we have the tools we need to respond effectively to these threats.
Dr. Camel's Conclusion
This research takes us on a journey through the vast desert of viral outbreaks, seeking out new weapons to combat the emerging threat of Monkeypox. The study reveals the potential for drug repurposing as a valuable strategy in the fight against this infectious disease. It's a reminder that the desert of medicine is full of hidden oases of knowledge, and we must always be vigilant and adaptable in our search for solutions to protect public health.
Date :
- Date Completed n.d.
- Date Revised 2022-11-17
Further Info :
Related Literature
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