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A Pilot Study of Transdermal Application of Diphenhydramine to the Nasal Ala in Patients with Allergic Rhinitis and Asthma.

Author: AsanoKoichiro, InuiToshiya, KamimuraMitsuhiro, MouriAtsuto, SugibayashiKenji, TodoHiroaki

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Transdermal application of diphenhydramine on the nasal ala for treating allergic rhinitis showed potential efficacy in certain patients but was not conclusive. Two patients experienced acute exacerbation of asthma during the intervention phase, suggesting a potential risk for patients with co-existing asthma.
Paper Details　
Original Abstract of the Article :
BACKGROUND: To date, topical allergic rhinitis drugs must be applied intranasally. We studied the efficacy, safety, and impact on co-existing asthma symptoms of transdermal delivery of diphenhydramine through the nasal ala. METHODS: We enrolled outpatients with symptomatic allergic rhinitis and ast...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/36420548

データ提供：米国国立医学図書館（NLM）

A New Approach to Allergic Rhinitis Treatment

Allergic rhinitis, a common condition that affects the nasal passages, can be a nuisance for many individuals. This study explores the potential of a novel approach to treating allergic rhinitis: transdermal delivery of diphenhydramine through the nasal ala. The researchers aim to assess the efficacy, safety, and impact on co-existing asthma symptoms of this method.

Transdermal Diphenhydramine: A Potential New Option for Allergic Rhinitis

The study found that transdermal application of diphenhydramine to the nasal ala appeared to be effective in treating nasal symptoms in some patients, but the results were not conclusive. The researchers suggest that further research is needed to determine the effectiveness and safety of this approach.

Exploring New Frontiers in Treatment: A Novel Approach to Allergic Rhinitis

Imagine a world where allergic rhinitis is treated with a simple and convenient transdermal application. This study provides a starting point for exploring the potential of this innovative approach, paving the way for future research and development of new treatment options for allergic rhinitis.

Dr.Camel's Conclusion

This research opens a new door in the field of allergic rhinitis treatment, exploring the potential of transdermal diphenhydramine delivery. It's like finding a hidden path in the desert of allergy research, leading to new possibilities for relief from this common condition.

Date :
  1. Date Completed 2022-11-25
  2. Date Revised 2022-11-25
Further Info :

Pubmed ID

36420548

DOI: Digital Object Identifier

36420548

Related Literature

Article Analysis
・Effects of diphenhydramine topical
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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