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Efficacy and safety of COVID-19 vaccines.

Author: AskieLisa M, AssiRouba, BergmanHanna, BonnetHillary, BoutronIsabelle, BuckleyBrian S, ChaimaniAnna, DavidsonMauricia, DevaneDeclan, EvrenoglouTheodoros, FerrandGabriel, GhosnLina, GrasselliGiacomo, GrañaCarolina, HenschkeNicholas, HróbjartssonAsbjørn, JardeAlexander, KredoTamara, LelievreJean-Daniel, MallonPatrick, MartiMelanie, MeerpohlJoerg J, MenonSonia, MinozziSilvia, ProbynKatrin, RadaGabriel, RavaudPhilippe, RiverosCarolina, ToveyDavid, VillanuevaGemma

ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

A review of 41 randomized controlled trials found that most COVID-19 vaccines reduce, or likely reduce, the proportion of participants with confirmed symptomatic COVID-19, and for some, there is high-certainty evidence that they reduce severe or critical disease. There is probably little or no difference between most vaccines and placebo for serious adverse events.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Different forms of vaccines have been developed to prevent the SARS-CoV-2 virus and subsequent COVID-19 disease. Several are in widespread use globally.  OBJECTIVES: To assess the efficacy and safety of COVID-19 vaccines (as a full primary vaccination series or a booster dose) against SA...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9726273/

データ提供：米国国立医学図書館（NLM）

COVID-19 Vaccines: Efficacy and Safety

The development and deployment of COVID-19 vaccines have been a monumental endeavor, akin to constructing an oasis in the middle of a scorching desert, offering hope and resilience in the face of a global crisis. This comprehensive review assessed the efficacy and safety of various COVID-19 vaccines, providing a comprehensive overview of their effectiveness in preventing SARS-CoV-2 infection and reducing the severity of COVID-19 disease. The authors conducted a thorough analysis of randomized controlled trials (RCTs) comparing different vaccines and vaccine schedules, evaluating their impact on critical outcomes such as symptomatic COVID-19, severe disease, and serious adverse events.

A Beacon of Hope in the COVID-19 Pandemic

The review found that most COVID-19 vaccines significantly reduced the incidence of symptomatic COVID-19 and severe disease compared to placebo. These findings, like a refreshing spring in the desert, provide a beacon of hope in the fight against the pandemic. The review also highlighted the reassuring safety profiles of most vaccines, suggesting that the benefits of vaccination far outweigh the risks for most individuals.

Navigating the Uncharted Territory of Pandemic Vaccination

This review, like a compass guiding travelers through uncharted desert terrain, provides essential information for navigating the complex landscape of COVID-19 vaccination. The findings underscore the crucial role of vaccines in mitigating the pandemic and highlight the importance of continued research and monitoring to ensure optimal efficacy and safety.

Dr.Camel's Conclusion

This comprehensive review, like a well-stocked caravan navigating a challenging desert journey, provides invaluable insights into the efficacy and safety of COVID-19 vaccines. The findings highlight the significant role of vaccines in protecting individuals and communities from the devastating effects of the pandemic, offering a ray of hope and resilience in the face of unprecedented global challenges.

Date :
  1. Date Completed 2022-12-15
  2. Date Revised 2023-09-12
Further Info :

Pubmed ID

36473651

DOI: Digital Object Identifier

PMC9726273

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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