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LC-MS/MS method for simultaneous quantification of ten antibiotics in human plasma for routine therapeutic drug monitoring.
Author: DayRichard O, GalettisPeter, JonesGraham D R, NorrisRoss L G, RadovanovicMirjana
Original Abstract of the Article :
Optimizing antimicrobial therapy to attain drug exposure that limits the emergence of resistance, effectively treats the infection, and reduces the risk of side effects is of a particular importance in critically ill patients, in whom normal functions are augmented or/and are infected with pathogens...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
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* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9756784/
データ提供:米国国立医学図書館(NLM)
Precision Antibiotic Therapy: A New Frontier
In the face of rising antibiotic resistance, optimizing antibiotic therapy is more important than ever. This research focuses on the development of a liquid chromatography tandem mass spectrometry (LC-MS/MS) method for simultaneous quantification of ten antibiotics in human plasma. This innovative approach aims to facilitate therapeutic drug monitoring (TDM), allowing clinicians to personalize antibiotic treatment based on individual patient needs. This research offers a valuable tool for optimizing antibiotic therapy and combating the growing threat of antibiotic resistance.
Optimizing Antibiotic Therapy: A Key to Combatting Resistance
This research highlights the importance of TDM in optimizing antibiotic therapy and combating the growing threat of antibiotic resistance. The development of a reliable LC-MS/MS method for simultaneous quantification of multiple antibiotics in human plasma provides a valuable tool for clinicians, enabling them to personalize treatment plans and achieve optimal drug exposure for each patient.
A Desert of Resistance: Navigating Antibiotic Therapy
Antibiotic resistance is a growing global health concern. This research offers a promising approach to tackling this challenge by enabling more precise and personalized antibiotic therapy. By optimizing drug exposure and monitoring treatment effectiveness, we can help to slow the spread of antibiotic resistance and improve patient outcomes.
Dr.Camel's Conclusion
This research offers a ray of hope in the fight against antibiotic resistance. The development of a new LC-MS/MS method for TDM provides a powerful tool for optimizing antibiotic therapy, ensuring that patients receive the right dose of the right drug at the right time. It's a testament to the ongoing efforts to develop innovative solutions to address this critical global health challenge.
Date :
- Date Completed n.d.
- Date Revised 2022-12-22
Further Info :
Related Literature
English
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