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Diuretics in pediatrics.

Author: ChehadeHassib, Di BernardoStefano, LavaSebastiano A G, SchaffnerDamien, SekarskiNicole, ZollingerChiara

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Diuretics are commonly prescribed drugs for managing various conditions, including kidney disease, heart failure, and hypertension. This educational article reviews the indications, mechanisms of action, side effects, and pharmacokinetics of diuretic classes, including osmotic diuretics, loop diuretics, thiazides, and potassium-sparing diuretics. It also discusses newer classes like vaptans and sodium glucose type 2 cotransporter inhibitors, controversies surrounding hydrochlorothiazide, and the issue of diuretic resistance. This comprehensive review aims to guide clinicians in selecting appropriate diuretic regimens for individual patients.
Paper Details　
Original Abstract of the Article :
Diuretics are frequently prescribed drugs and help managing several pathological conditions, including acute and chronic kidney disease, nephrotic syndrome, congestive heart failure, ascites, systemic and pulmonary hypertension. Diuretic classes include among others osmotic diuretics and carboanhydr...See full text at original site
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引用元：
https://doi.org/10.1007/s00431-022-04768-2

データ提供：米国国立医学図書館（NLM）

Diuretics: A Lifeline for Little Ones

The field of pediatrics is constantly evolving, and understanding the use of diuretics in children is a crucial aspect. This research dives deep into the use of diuretics, which are frequently prescribed for various conditions in children, including kidney disease, nephrotic syndrome, and heart failure. The authors meticulously investigated the indications, mechanisms of action, and side effects of diuretics. They also explored the pharmacokinetics of these drugs in children, providing valuable insights for clinicians to make informed decisions about diuretic treatment regimens.

Navigating the Landscape of Diuretics

This research sheds light on the diverse classes of diuretics, including osmotic diuretics, loop diuretics, thiazides, and potassium-sparing diuretics. The authors also highlight the importance of understanding newer diuretic classes like vaptans and sodium glucose type 2 cotransporter inhibitors, which are gaining traction in the medical world. They also discuss the recent controversies surrounding hydrochlorothiazide and the challenge of diuretic resistance. This thorough investigation serves as a guide for clinicians to navigate the complex world of diuretics in children.

When the Little Ones Need a Helping Hand

Understanding the benefits and risks of diuretics is essential in pediatric care. Clinicians can leverage this research to make informed decisions about diuretic treatment regimens for their young patients. This research emphasizes the importance of individualizing treatment plans to ensure the best possible outcomes for children.

Dr. Camel's Conclusion

Diuretics are powerful tools in the physician's arsenal for treating a variety of conditions in children. By understanding the mechanisms of action, potential side effects, and pharmacokinetic considerations, clinicians can make informed choices about diuretic treatment regimens. This research serves as a valuable guide for navigating the complex world of diuretics in pediatric medicine. It's like navigating a vast desert - you need a reliable compass and a map to guide you, and this research provides both.

Date :
  1. Date Completed 2023-05-15
  2. Date Revised 2023-05-15
Further Info :

Pubmed ID

36595088

DOI: Digital Object Identifier

10.1007/s00431-022-04768-2

SNS
PICO Info
in preparation
Languages

English

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