Cost-effectiveness of cenobamate for focal seizures in people with drug-resistant epilepsy.

Author: Agyei-KyerematengKenneth K, EddyAlex E, JamesSamuel, LaskierVicki, MulheronStuart, PatelDilip, SanderJosemir W, ThomasRhys H

Paper Details 
Original Abstract of the Article :
OBJECTIVE: This study was undertaken to estimate the cost-effectiveness of add-on cenobamate in the UK when used to treat drug-resistant focal seizures in adults who are not adequately controlled with at least two prior antiseizure medications, including at least one used adjunctively. METHODS: We ...See full text at original site
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引用元:
https://doi.org/10.1111/epi.17506

データ提供:米国国立医学図書館(NLM)

Cenobamate: A Potential Oasis in the Desert of Drug-Resistant Epilepsy

The treatment of drug-resistant epilepsy often feels like navigating a vast, unforgiving desert, with patients searching for an oasis of relief. This study explores the cost-effectiveness of cenobamate, a new antiseizure medication, as an add-on therapy for individuals whose seizures are not adequately controlled by existing treatments. The researchers employed a Markov cohort model to compare the cost-effectiveness of cenobamate to other antiseizure medications, including brivaracetam, eslicarbazepine, lacosamide, and perampanel. They considered various factors such as treatment response, adverse events, and quality-adjusted life years (QALYs).

A Promise of Relief: Cenobamate Demonstrates Cost-Effectiveness in Treating Drug-Resistant Epilepsy

The study found that cenobamate led to significant cost savings and an increase in QALYs compared to the other medications. This suggests that cenobamate may be a more cost-effective and beneficial treatment option for individuals with drug-resistant focal seizures. The study's findings provide valuable insight into the potential of cenobamate as a viable treatment option for patients with drug-resistant epilepsy, offering hope for a brighter future.

Navigating the Desert of Epilepsy Treatment: Exploring New Treatment Strategies

This research highlights the importance of exploring new treatment options for drug-resistant epilepsy, a condition that often presents significant challenges for patients and healthcare providers. Cenobamate's cost-effectiveness and potential for improving QALYs suggests a promising new avenue for treatment, potentially leading to a more effective and personalized approach to managing this complex condition.

Dr.Camel's Conclusion

This study presents a beacon of hope in the desert of drug-resistant epilepsy, suggesting that cenobamate may offer a cost-effective and beneficial treatment option. By providing a more effective means of managing seizures and improving QALYs, cenobamate may bring much-needed relief and enhance the quality of life for individuals struggling with this challenging condition.

Date :
  1. Date Completed 2023-04-14
  2. Date Revised 2023-04-17
Further Info :

Pubmed ID

36625423

DOI: Digital Object Identifier

10.1111/epi.17506

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Languages

English

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