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Thiazide diuretics are back in CKD: the case of chlorthalidone.

Author: De NicolaLuca, MallamaciFrancesca, MinutoloRoberto, ZoccaliCarmine

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This review appraises published randomized trials of thiazide diuretics in chronic kidney disease (CKD) patients. Despite long-held beliefs about their limited efficacy in advanced CKD, thiazides may be useful in this population, especially for treatment-resistant hypertension.
Paper Details　
Original Abstract of the Article :
Sodium and volume excess is the fundamental risk factor underlying hypertension in chronic kidney disease (CKD) patients, who represent the prototypical population characterized by salt-sensitive hypertension. Low salt diets and diuretics constitute the centrepiece for blood pressure control in CKD....See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871852/

データ提供：米国国立医学図書館（NLM）

Thiazide Diuretics in Chronic Kidney Disease: A New Perspective

This study reviews the current evidence regarding the use of thiazide diuretics in patients with chronic kidney disease (CKD). The authors discuss the role of thiazide diuretics in managing hypertension, particularly in the context of advanced CKD, and highlight the potential benefits of these drugs in this population. The study also emphasizes the importance of careful monitoring and management of potential side effects associated with thiazide diuretics.

Rethinking Thiazide Diuretics: A New Oasis in the Desert of CKD Treatment

This study re-examines the role of thiazide diuretics in managing hypertension in patients with CKD. The authors provide a compelling review of the literature, highlighting the potential benefits of these drugs, particularly in the context of advanced CKD. It's like discovering a hidden oasis in the vast desert of CKD treatment, where new solutions are being explored to manage hypertension and improve patient outcomes.

Managing Chronic Kidney Disease: A Journey Through the Desert of Health Challenges

The results of this study emphasize the importance of a comprehensive approach to managing CKD, including careful monitoring of blood pressure and the use of appropriate medications. Healthcare professionals should be aware of the potential benefits and risks associated with thiazide diuretics and make informed decisions based on individual patient needs. Remember, just as a camel navigates the harsh desert environment, we need to be resourceful and adaptable in managing the challenges of CKD.

Dr. Camel's Conclusion

This study provides a valuable review of the current evidence regarding the use of thiazide diuretics in patients with CKD. The findings highlight the potential benefits of these drugs in managing hypertension, particularly in the context of advanced CKD. It's a reminder that the field of CKD treatment is constantly evolving, with new insights and approaches emerging to improve patient outcomes. Just like a camel adapting to the ever-changing desert landscape, we need to stay informed and embrace innovation in our pursuit of better health.
Date :
  1. Date Completed n.d.
  2. Date Revised 2023-02-03
Further Info :

Pubmed ID

36726437

DOI: Digital Object Identifier

PMC9871852

Related Literature

Article Analysis
・Side Effects of chlorthalidone
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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