Paper Details 
Original Abstract of the Article :
Psychotic symptoms are reported as one of the most common complications of Alzheimer's disease (AD), affecting approximately half of AD patients, in whom they are associated with more rapid deterioration and increased mortality. Empiric treatments, namely first and second-generation antipsychotics, ...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9901071/

データ提供:米国国立医学図書館(NLM)

A Novel Combination Therapy for Psychosis in Alzheimer's Disease: Antidepressants and Antipsychotics

Alzheimer's disease (AD), a progressive neurodegenerative disorder, often manifests with debilitating psychotic symptoms, significantly impacting patient care and quality of life. This research explores the potential of combining antidepressants with antipsychotics as a novel treatment approach for psychosis in AD patients (AD+P). The authors note that while antipsychotics have been the mainstay treatment for AD+P, they often confer modest efficacy and carry an increased risk of mortality. Recent studies suggest that antidepressants may offer therapeutic benefits for AD+P, motivating the exploration of combination therapy. The authors propose a rationale for exploring the potential of combining antidepressants and antipsychotics as a novel treatment option for AD+P, based on emerging research findings and the need for safer and more effective therapeutic strategies.

A New Dawn in AD+P Treatment: Exploring Combination Therapies

The research presents a compelling argument for investigating the combination of antidepressants and antipsychotics as a potentially more effective and safer treatment for AD+P. The authors emphasize the urgent need for novel therapeutic approaches to address the significant challenges posed by psychosis in Alzheimer's disease.

Navigating the Desert of Alzheimer's Disease: A Quest for Improved Therapies

Alzheimer's disease is a complex and devastating condition, and psychosis adds further complications to patient care. This research highlights the importance of ongoing research to develop safer and more effective treatment options for AD+P, offering hope for improved outcomes for patients and their families.

Dr.Camel's Conclusion

The desert of Alzheimer's disease is a formidable landscape, and psychosis adds another layer of complexity. This research offers a glimmer of hope for improved treatment strategies, emphasizing the importance of continuous innovation in the quest for effective therapies for AD+P.

Date :
  1. Date Completed n.d.
  2. Date Revised 2023-11-11
Further Info :

Pubmed ID

36747620

DOI: Digital Object Identifier

PMC9901071

Related Literature

SNS
PICO Info
in preparation
Languages

English

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