Paper Details 
Original Abstract of the Article :
<b>Overview of:</b> Kim BK, Hong SJ, Lee YJ, <i>et al</i> Long-term efficacy and safety of moderate-intensity statin with ezetimibe combination therapy versus high-intensity statin monotherapy in patients with atherosclerotic cardiovascular disease (RACING): a randomised, open-label, non-inferiorit...See full text at original site
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引用元:
https://doi.org/10.1136/dtb.2023.000008

データ提供:米国国立医学図書館(NLM)

Ezetimibe and Statins: A New Approach to Cholesterol Management

Atherosclerotic cardiovascular disease (ASCVD) is a leading cause of morbidity and mortality worldwide. This study investigates the long-term efficacy and safety of a combination therapy using ezetimibe and a moderate-intensity statin versus high-intensity statin monotherapy in patients with ASCVD. The study aims to determine if this combination therapy offers a safe and effective alternative for cholesterol management.

Combination Therapy's Promise for Cholesterol Management

The study's findings suggest that ezetimibe combined with a moderate-intensity statin is non-inferior to high-intensity statin monotherapy in terms of efficacy and safety. This finding has significant implications for personalized medicine, providing a potentially more tolerable treatment option for individuals with ASCVD.

Personalized Medicine: Tailoring Treatment to Individual Needs

Think of cholesterol as a sand dune in the desert, gradually building up and obstructing blood flow. This study explores the potential of different approaches to manage these sand dunes, by comparing high-intensity statins to a combination of ezetimibe and moderate-intensity statins. The study's findings point towards a more personalized approach to cholesterol management, recognizing that different individuals may respond better to different treatment strategies.

Dr.Camel's Conclusion

The study's findings offer a new perspective on cholesterol management, providing a potential alternative for individuals who may not tolerate high-intensity statins well. This research is a testament to the power of personalized medicine, recognizing that the most effective treatment strategies are often tailored to individual needs and preferences.

Date :
  1. Date Completed 2023-02-24
  2. Date Revised 2023-02-24
Further Info :

Pubmed ID

36813278

DOI: Digital Object Identifier

10.1136/dtb.2023.000008

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SNS
PICO Info
in preparation
Languages

English

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