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The mechanistic effects of human digestion on magnesium oxide nanoparticles: implications for probiotics Lacticaseibacillus rhamnosus GG and Bifidobacterium bifidum VPI 1124.
Author: García-RodríguezAlba, KolbaNikolai, LimageRhodesherdeline, MahlerGretchen J, MarquesCláudia N H, StillwellAllayah, TakoElad, TanzmanJacob V, TochilovskyBlake
Original Abstract of the Article :
The effects of nanoparticles (NPs) on the human gut microbiota are of high interest due to the link between the gut homeostasis and overall human health. The human intake of metal oxide NPs has increased due to its use in the food industry as food additives. Specifically, magnesium oxide nanoparticl...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://pubmed.ncbi.nlm.nih.gov/36874593
データ提供:米国国立医学図書館(NLM)
The Unexpected Impact of Magnesium Oxide Nanoparticles on Gut Microbiota
The human gut is a teeming desert of microorganisms, playing a vital role in our health. This study investigates the impact of magnesium oxide nanoparticles (MgO-NPs), a common food additive, on the gut microbiome. The researchers analyzed the effects of MgO-NPs on two key gut bacteria: Lactobacillus rhamnosus GG and Bifidobacterium bifidum VPI 1124.
MgO-NPs: A Complex Interaction with Gut Bacteria
The study found that MgO-NPs, after undergoing simulated digestion, released magnesium ions (Mg2+) that surprisingly increased the viability of both Lactobacillus rhamnosus and Bifidobacterium bifidum when they formed biofilms. Interestingly, high doses of MgO-NPs stimulated biofilm development in Lactobacillus rhamnosus but not Bifidobacterium bifidum. This research highlights the complex interplay between nanoparticles and gut bacteria.
Navigating the Unseen Landscape of Nanoparticles and Gut Health
This study reminds us that the impact of nanoparticles on gut health is a vast and often unseen landscape. It emphasizes the need for further research into the long-term effects of nanoparticles on the delicate balance of our gut microbiome.
Dr.Camel's Conclusion
This study reveals that the desert of the human gut holds secrets that are still being uncovered. The interaction between MgO-NPs and gut bacteria is a complex dance, with unexpected outcomes. This research encourages us to be mindful of the potential impact of food additives on our gut health, while also inspiring further investigations into the fascinating world of nanoparticles and their interactions with our bodies.
Date :
- Date Completed n.d.
- Date Revised 2023-12-02
Further Info :
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