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Efficacy and safety of direct oral anticoagulants versus vitamin K antagonists for left ventricular thrombus: an updated systematic review and meta-analysis.

Author: BerdibekovB Sh, GolukhovaE Z, RuzinaE V

Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This systematic review and meta-analysis compares the efficacy and safety of direct oral anticoagulants (DOAC) and vitamin K antagonists (VKA) in treating left ventricular (LV) thrombosis. The analysis shows no significant differences between DOAC and VKA in terms of thromboembolic events, hemorrhagic complications, and thrombus resolution. However, rivaroxaban showed a significant reduction in thromboembolic complications compared to VKA.
Paper Details　
Original Abstract of the Article :
Aim    To perform a systematic review and meta-analysis of efficacy and safety of direct oral anticoagulants (DOAC) as compared to vitamin K antagonists (VKA) in the treatment of left ventricular (LV) thrombosis.Material and methods    A search was performed in PubMed and Google Scholar for studies ...See full text at original site
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引用元：
https://doi.org/10.18087/cardio.2023.2.n2200

データ提供：米国国立医学図書館（NLM）

Direct Oral Anticoagulants vs. Vitamin K Antagonists for Left Ventricular Thrombus: A Comparative Analysis

The world of [cardiology] is constantly evolving, with researchers striving to find the most effective and safe treatments for cardiovascular conditions. This study compares the efficacy and safety of [direct oral anticoagulants (DOACs)] and [vitamin K antagonists (VKAs)] in the treatment of [left ventricular (LV) thrombosis].

The researchers conducted a systematic review and meta-analysis of studies comparing DOACs and VKAs for LV thrombosis. They found no significant difference in efficacy or safety between the two treatment groups with respect to thromboembolic events, hemorrhagic complications, and thrombus resolution. However, they did note that rivaroxaban, a specific DOAC, was associated with a reduced risk of thromboembolic complications compared to VKAs.

DOACs and VKAs: Evaluating Efficacy and Safety

This research, like a camel navigating a vast desert, explores the intricate landscape of anticoagulation therapies. The findings suggest that both DOACs and VKAs can be effective in treating LV thrombosis, with rivaroxaban potentially offering a greater benefit in reducing thromboembolic events.

Choosing the Right Anticoagulant Therapy

Just as a camel adapts to the varying terrain of the desert, choosing the right anticoagulant therapy for LV thrombosis requires careful consideration of individual patient factors. This research provides valuable information for healthcare providers to make informed decisions about anticoagulation therapy.

Dr.Camel's Conclusion

This study, like a caravan navigating a desert with multiple pathways, offers a comprehensive comparison of DOACs and VKAs for LV thrombosis. The findings provide valuable insights into the efficacy and safety of these treatments, helping healthcare providers make informed decisions to optimize patient care.

Date :
  1. Date Completed 2023-03-08
  2. Date Revised 2023-03-08
Further Info :

Pubmed ID

36880139

DOI: Digital Object Identifier

10.18087/cardio.2023.2.n2200

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Languages

Russian

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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