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Thrombocytopenia during avacopan administration: A case report.
Author: AkagiYuichiro, AndoFumiaki, FujikiTamami, HaniokaAsami, IimoriSoichiro, MandaiShintaro, MoriKatsuo, MoriTakayasu, MoriYutaro, MorimotoNobuhisa, NaitoShotaro, SakaiKeigo, ShiojiShingo, SoharaEisei, SusaKoichiro, UchidaShinichi, WatanabeHatsumi, YamamuraAyumi
Original Abstract of the Article :
Avacopan is a novel C5a receptor antagonist recently approved for the treatment of microscopic polyangiitis and granulomatosis with polyangiitis. To our knowledge, thrombocytopenia induced by avacopan has not been reported. We report a case of a 78-year-old man with microscopic polyangiitis who deve...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1111/1756-185X.14645
データ提供:米国国立医学図書館(NLM)
A New Oasis in Vasculitis Treatment: Avacopan and a Case of Thrombocytopenia
The desert of vasculitis treatment is a challenging terrain, requiring a careful exploration of new therapeutic approaches. This case report, like a lone traveler venturing into uncharted territory, describes the experience of a patient with [microscopic polyangiitis] who developed thrombocytopenia during treatment with [avacopan], a novel C5a receptor antagonist. The doctors, like seasoned explorers, meticulously documented the patient's condition and the potential role of avacopan in the development of thrombocytopenia. This case highlights the importance of postmarketing surveillance to identify potential side effects of new medications.
Navigating the Desert of New Medications
This case report, like a warning sign in a desert, underscores the importance of careful monitoring of new medications. While avacopan shows promise in treating vasculitis, this case reminds us that even the most promising treatments can have unexpected side effects. Postmarketing surveillance is crucial in ensuring the safety and efficacy of new medications.
The Importance of Vigilance in Healthcare
This case report emphasizes the importance of vigilance in healthcare. It's a reminder that even as we explore new oases of treatment, we must remain alert to potential dangers in the desert of medical practice. Careful monitoring and open communication between patients and doctors are crucial in ensuring the safety and well-being of everyone.
Dr. Camel's Conclusion
This case report underscores the crucial need for ongoing vigilance in the desert of healthcare. While avacopan shows promise in treating vasculitis, this case reminds us that even the most promising treatments can have unexpected side effects. By meticulously documenting and analyzing these cases, we can ensure a safer journey for patients and continue to improve our understanding of new medications.
Date :
- Date Completed 2023-10-23
- Date Revised 2023-10-23
Further Info :
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English
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