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Case report: Complete and durable response to larotrectinib (TRK inhibitor) in an infant diagnosed with angiosarcoma harbouring a <i>KHDRBS1-NTRK3</i> fusion gene.
Author: BedicsGábor, BödörCsaba, CerviCatherine, CsókaMonika, DezsőKatalin, HegyiLajos, MudraKatalin, PápayJudit, SápiZoltán, VargaEdit, ZajtaErik
Original Abstract of the Article :
Significant improvements in the survival rates of paediatric cancer have been achieved over the past decade owing to recent advances in therapeutic and diagnostic strategies. However, disease progression and relapse remain a major challenge for the clinical management of paediatric angiosarcoma. Com...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9997097/
データ提供:米国国立医学図書館(NLM)
Precision Medicine Triumphs: Complete Remission of Angiosarcoma in an Infant
This research is a testament to the transformative power of precision medicine. It's like a detective story where researchers use advanced technology to identify the root cause of a rare and aggressive cancer, angiosarcoma, in an infant. They've uncovered a hidden culprit: a KHDRBS1-NTRK3 fusion gene. Think of it as a genetic puzzle, where the pieces have been rearranged, leading to an unexpected outcome. Armed with this knowledge, they've devised a targeted treatment using larotrectinib, a drug that specifically targets the NTRK3 fusion gene. This is like finding a specific antidote for a rare poison, providing a lifeline for a child with a life-threatening condition.
A New Era of Precision Medicine: Targeting Cancer with Molecular Precision
This research is like a beacon of hope in the dark desert of cancer treatment. The complete and durable response to larotrectinib in this infant demonstrates the remarkable potential of precision medicine, allowing doctors to tailor treatments to the specific molecular profiles of each patient. It's like unlocking the secrets of a hidden treasure chest, revealing new strategies for fighting cancer with unprecedented accuracy.
A Hopeful Future for Cancer Treatment: The Promise of Precision Medicine
Just as a camel relies on its innate ability to navigate the desert, we are relying on the power of precision medicine to navigate the challenges of cancer. This remarkable case exemplifies the potential of targeted therapies and personalized medicine to deliver life-saving treatments. It's a reminder that with continued research and technological advancements, we can create a future where cancer is no longer a death sentence, but a treatable disease.
Dr.Camel's Conclusion
This research is like a shimmering oasis in the vast and unforgiving desert of childhood cancer. By highlighting the effectiveness of targeted therapies and the promise of precision medicine, it offers a ray of hope for patients battling this devastating disease. It's a testament to the power of scientific inquiry and the potential of human ingenuity to transform healthcare and create a brighter future for those in need.
Date :
- Date Completed n.d.
- Date Revised 2023-03-14
Further Info :
Related Literature
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