Opioids in the Treatment of Chronic Idiopathic Diarrhea in Humans-A Systematic Review and Treatment Guideline.

Author: DrewesAsbjørn M, Graven-NielsenChristoffer S, HellströmPer M, HøyerKatrine L, KnophCecilie S, KroghKlaus, OkdahlTina

Paper Details 
Original Abstract of the Article :
In patients with chronic idiopathic diarrhea resistant to standard treatment, opioids are often used as rescue therapy. This systematic review investigated opioid effects on gut function in chronic diarrhea. PubMed and Embase were searched regarding effects of opioid agonists on the gastrointestinal...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094889/

データ提供:米国国立医学図書館(NLM)

Opioids for Chronic Idiopathic Diarrhea

This study explores the use of opioids in treating chronic idiopathic diarrhea, a condition characterized by persistent and unexplained diarrhea. It's like searching for a solution to a mysterious desert drought, seeking to understand the root cause and find a way to alleviate the symptoms. The study focuses on opioid agonists, a class of medications that bind to opioid receptors in the body.

Opioids May Provide Relief for Chronic Idiopathic Diarrhea

The study found that opioid agonists, such as loperamide, asimadoline, casokefamide, and codeine, were effective in reducing stool frequency and increasing transit time in patients with chronic diarrhea. This is like finding a water source in a parched desert, providing temporary relief from the discomfort of persistent diarrhea. However, the study also emphasizes the need for further research to confirm these findings and to develop standardized measures for evaluating the effectiveness of opioids in this context.

Opioids May Offer Potential Benefits for Chronic Diarrhea, but More Research is Needed

The study suggests that opioids may offer a potential treatment option for chronic idiopathic diarrhea, but further research is needed to confirm their effectiveness and safety. It's like a desert explorer finding a promising trail, but needing to explore it further before confirming its suitability for a long journey.

Dr.Camel's Conclusion

This research is like a camel caravan searching for an oasis in the desert of chronic idiopathic diarrhea. While opioids may offer temporary relief, more research is needed to understand their long-term effects and to develop more effective and safe treatment options. The journey to a cure is long and complex, but research provides the compass and guide for finding the best solutions.

Date :
  1. Date Completed n.d.
  2. Date Revised 2023-04-15
Further Info :

Pubmed ID

37048572

DOI: Digital Object Identifier

PMC10094889

Related Literature

SNS
PICO Info
in preparation
Languages

English

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