Inhibitory and in silico molecular docking of Xeroderris stuhlmannii (Taub.) Mendonca & E.P. Sousa phytochemical compounds on human α-glucosidases.

Author: BvunzawabayaJonathan Tatenda, ManzombeEmily, MunyukiGadzikano, NyathiBrilliant, RwereFreeborn, SelemaniMajor Allen, TsotsoroKudakwashe, Venissa P MudawarimaChido

Paper Details 
Original Abstract of the Article :
Herbal traditional medicine is used by millions of people in Africa for treatment of ailments such as diabetes mellitus, stomach disorders and respiratory diseases. Xeroderris stuhlmannii (Taub.) Mendonca & E.P. Sousa (X. stuhlmannii (Taub.)) is a medicinal plant used traditionally in Zimbabwe to tr...See full text at original site
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引用元:
https://doi.org/10.1016/j.jep.2023.116501

データ提供:米国国立医学図書館(NLM)

Xeroderris stuhlmannii: A Potential Antidiabetic Remedy?

Traditional herbal medicine, deeply rooted in the cultures of many regions, offers a vast repository of potential therapeutic agents. This study investigates the potential of [Xeroderris stuhlmannii], a medicinal plant used traditionally in [Zimbabwe] to treat [type 2 diabetes mellitus (T2DM)], as a [α-glucosidase inhibitor].

The Role of α-Glucosidases in Diabetes

The authors focus on the role of [α-glucosidases], enzymes that contribute to the breakdown of [carbohydrates] and [blood sugar regulation]. The study explores the potential of [X. stuhlmannii] to inhibit these enzymes, suggesting its potential role in [diabetes management].

Harnessing Nature's Potential for Health

The study highlights the importance of [scientific validation] of traditional remedies. Like a careful camel, we must explore the potential of nature's bounty with a discerning eye, seeking to understand its true value. This research provides a foundation for further investigations into the potential of [X. stuhlmannii] as a [natural therapeutic agent] for [T2DM] and its associated complications.

Dr.Camel's Conclusion

This research delves into the potential of Xeroderris stuhlmannii as a natural therapeutic agent for diabetes, offering hope for the development of new treatments based on traditional remedies. The study's focus on α-glucosidase inhibition presents a promising avenue for future research, highlighting the interconnectedness between traditional wisdom and scientific exploration in the quest for better health. Remember, just as a camel navigates the desert landscapes, we must traverse the vast expanse of knowledge to unlock the secrets of nature's healing power.
Date :
  1. Date Completed 2023-05-08
  2. Date Revised 2023-05-08
Further Info :

Pubmed ID

37100261

DOI: Digital Object Identifier

10.1016/j.jep.2023.116501

Related Literature

SNS
PICO Info
in preparation
Languages

English

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