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Management of amlodipine-induced ankle oedema

Author: ChristensenBo, HelgestadOle Kl, HenriksenJakob N, OxlundChristina S, SkovbjergBirgit K

ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This review provides an overview of management strategies for pedal edema, a common side effect of amlodipine, a calcium channel blocker. The review prioritizes strategies to minimize side effects, including reducing dosage, switching to alternative calcium channel blockers, adding ACE inhibitors or angiotensin II-receptor blockers, and administering the drug at night.
Paper Details　
Original Abstract of the Article :
Pedal oedema is a well-known adverse effect of amlodipine, but significantly less frequent if only half of the maximum recommended dosage is used. Diuretics are ineffective. To cause as few side effects as possible, options for managing are prioritised in this review: Reduce dosage, switch to lercan...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/37114573

データ提供：米国国立医学図書館（NLM）

Amlodipine and Pedal Edema: A Quest for Optimal Dosage and Management

The [pharmacology] of cardiovascular medications is a complex and ever-evolving field. This research explores the common side effect of pedal edema (swelling in the feet and ankles) associated with the calcium channel blocker amlodipine. The authors delve into strategies for managing this side effect, seeking to minimize its impact on patients' lives.

Navigating the Side Effects of Amlodipine

The study confirms that pedal edema is a known side effect of amlodipine, but it also reveals a crucial insight: reducing the dosage to half of the maximum recommended level significantly reduces the frequency of this side effect. The authors also dispel a common misconception, demonstrating that diuretics are ineffective in addressing amlodipine-induced pedal edema. This study offers practical guidance for clinicians in managing amlodipine therapy, emphasizing the importance of individualizing dosage and exploring alternative strategies when necessary.

Finding the Right Path for Optimal Well-being

Understanding the potential side effects of medications, much like navigating the shifting sands of the desert, requires careful consideration and a thoughtful approach. The study provides valuable insights into managing amlodipine-induced pedal edema, offering a range of strategies that can help patients maintain their cardiovascular health while minimizing discomfort. From dosage adjustments to alternative medications, the study provides a comprehensive guide for achieving optimal well-being.

Dr. Camel's Conclusion

This research delves into the intricate world of amlodipine therapy, highlighting the importance of managing pedal edema, a common side effect. The study's findings provide valuable guidance for clinicians, emphasizing the need for personalized dosage adjustments and exploring alternative therapeutic options when necessary. This research underscores the importance of a proactive approach to patient care, ensuring that patients experience the benefits of amlodipine while minimizing discomfort and potential side effects.
Date :
  1. Date Completed 2023-05-01
  2. Date Revised 2023-05-01
Further Info :

Pubmed ID

37114573

DOI: Digital Object Identifier

V07220460

SNS
PICO Info
in preparation
Languages

Danish

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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