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Everolimus is Safe as a Second-/Third-Line Therapy in Pediatric Autoimmune Hepatitis.
Author: JannoneGiulia, M SokalEtienne, ScheersIsabelle, SmetsFrançoise, StephenneXavier
Original Abstract of the Article :
Autoimmune hepatitis (AIH) can lead to progressive fibrosis in patients refractory to conventional therapy with prednisolone and azathioprine. The use of mammalian target of rapamycin (mTOR) inhibitors has recently emerged in refractory AIH, but no data have been published about everolimus in pediat...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10158283/
データ提供:米国国立医学図書館(NLM)
Everolimus: A New Oasis in the Desert of Refractory Autoimmune Hepatitis
In the vast desert of autoimmune hepatitis (AIH), a condition where the immune system attacks the liver, finding effective treatments can be like searching for an elusive oasis. This study explores the use of everolimus, a mammalian target of rapamycin (mTOR) inhibitor, as a second- or third-line therapy for pediatric AIH. Researchers, like seasoned desert explorers, investigated the safety and efficacy of everolimus in children with AIH who had not responded well to conventional treatments. Their findings suggest that everolimus is a safe and potentially effective treatment option for pediatric AIH, offering a glimmer of hope in this challenging landscape.
A Promising Oasis: Everolimus in Pediatric AIH
This study provides encouraging evidence for the potential of everolimus as a safe and potentially effective treatment option for pediatric AIH. The researchers found that everolimus was well-tolerated by children with AIH and showed promising results in terms of controlling the disease. This suggests that everolimus could be a valuable addition to the arsenal of treatments for AIH in children.
Navigating the Desert of AIH: Seeking Specialized Care
Autoimmune hepatitis is a complex condition that requires specialized care. If you or your child are diagnosed with AIH, it's essential to seek guidance from a healthcare professional with experience in managing this disease. This study highlights the importance of exploring all treatment options, including newer therapies like everolimus. Remember, navigating the desert of AIH is best done with the support of a knowledgeable guide.
Dr.Camel's Conclusion
This study offers a beacon of hope in the desert of refractory autoimmune hepatitis. Everolimus, an mTOR inhibitor, shows promise as a safe and potentially effective treatment option for pediatric AIH. This research reminds us that the journey through the desert of illness is often a collaborative one, requiring the expertise of healthcare professionals and the determination of patients.
Date :
- Date Completed n.d.
- Date Revised 2023-05-14
Further Info :
Related Literature
English
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