Daily vs. monthly oral vitamin D<sub>3</sub> for treatment of symptomatic vitamin D deficiency in infants: a randomized controlled trial.

Author: DebnathEkta, GoraAnupriya, MalhotraRajeev Kumar, SethAnju, SinghPreeti

Paper Details 
Original Abstract of the Article :
OBJECTIVES: Compare the efficacy and safety of daily vs. monthly oral vitamin D METHODS: 90 infants with symptomatic vitamin D deficiency were randomized into Daily (D) [46 infants] and Bolus (B) [44 infants] groups to receive oral vitamin D RESULTS: Both regimens led to a statistically significan...See full text at original site
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引用元:
https://doi.org/10.1515/jpem-2023-0146

データ提供:米国国立医学図書館(NLM)

Vitamin D: Daily Dose or Monthly Boost?

The field of infant health is vast, and the quest for optimal vitamin D supplementation continues to be a hot topic. This study delves into the efficacy and safety of two different approaches to vitamin D administration in infants with diagnosed vitamin D deficiency. Researchers employed a randomized controlled trial, pitting daily vitamin D supplementation against a monthly bolus dose.

A Tale of Two Regimens

The results suggest that both daily and monthly vitamin D regimens were effective in increasing calcium and phosphorus levels, while simultaneously reducing alkaline phosphatase and parathyroid hormone levels. However, the daily regimen emerged as the winner, demonstrating statistically significant higher vitamin D levels in infants at both 4 and 12 weeks.

Sun, Sand, and Supplementation

This study provides valuable insights for parents and healthcare providers alike. While both methods are effective, the daily approach may offer a more consistent and potentially favorable outcome for infants battling vitamin D deficiency. Remember, sunlight remains a critical source of vitamin D, but supplementation plays a crucial role in ensuring adequate levels, particularly in infants.

Dr. Camel's Conclusion

This study is like a camel caravan traversing the vast desert of infant health, offering a clear path for optimal vitamin D supplementation. Daily doses seem to be the preferred route, but it’s important to remember that all infants are unique, and individual needs should be considered.

Date :
  1. Date Completed 2023-07-10
  2. Date Revised 2023-07-18
Further Info :

Pubmed ID

37192500

DOI: Digital Object Identifier

10.1515/jpem-2023-0146

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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