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Adverse Event Profile of Azacitidine: Analysis by Route of Administration Using Japanese Pharmacovigilance Database.

Author: FujiwaraMasaki, MuroiNobuyuki, ShimizuTadashi, UchidaMayako, UesawaYoshihiro, YamaokaKenta

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study examines azacitidine-induced adverse events (AEs) using the Japanese Adverse Event Reporting Database (JADER). It analyzes the time to onset of high-risk AEs, subsequent outcomes, and differences in AE frequency based on the route of administration.
Paper Details　
Original Abstract of the Article :
Azacitidine is a useful drug for myelodysplastic syndromes and acute myeloid leukemia. In clinical trials, hematologic toxicity and infection have been observed as adverse events (AEs) of this drug. However, information on the time to onset of high risk AEs and subsequent outcomes, as well as differ...See full text at original site
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引用元：
https://doi.org/10.1159/000531390

データ提供：米国国立医学図書館（NLM）

Azacitidine: A Powerful Drug with Side Effects

This study analyzes the adverse event profile of azacitidine, a drug used to treat myelodysplastic syndromes and acute myeloid leukemia, using data from the Japanese Adverse Event Reporting Database. It's like exploring a desert oasis, carefully examining both its beauty and its potential dangers.

Understanding the Risks

The study identified hematologic toxicity and infection as common adverse events associated with azacitidine, highlighting the need for careful monitoring and management of these potential complications. It's like recognizing the potential dangers of a desert oasis – the beauty comes with a price.

Route of Administration: A Key Factor

The study also explored differences in adverse events based on the route of administration of azacitidine, suggesting that different delivery methods might have varying risks and benefits. It's like choosing the best route through a desert landscape – different paths might have different challenges and advantages.

Dr.Camel's Conclusion

This research provides valuable insights into the adverse event profile of azacitidine, highlighting the importance of careful patient monitoring and understanding the risks associated with this powerful drug. It reminds us that even in the quest for effective therapies, it's crucial to weigh potential benefits against potential risks.
Date :
  1. Date Completed 2023-10-10
  2. Date Revised 2023-10-10
Further Info :

Pubmed ID

37279701

DOI: Digital Object Identifier

10.1159/000531390

Related Literature

Article Analysis
・Side Effects of azacitidine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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