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[Therapy of duodenal and prepyloric ulcers with cimetidine (author's transl)].

Author: HavelecL, HentschelE, SchützeK

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Cimetidine was more effective than placebo in healing duodenal ulcers. In a double-blind randomized trial, 73% of patients on cimetidine showed complete ulcer healing after 4 weeks compared to 32% of those on placebo.
Paper Details　
Original Abstract of the Article :
In a double-blind randomized trial 91 patients with endoscopically confirmed duodenal and/or prepyloric ulcers received either 1000 mg cimetidine daily (44 patients) or placebo (47 patients) for 4 weeks. At 2 weeks complete ulcer healing was significantly increased in patients receiving cimetidine (...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/373260

データ提供：米国国立医学図書館（NLM）

Cimetidine: A Oasis in the Desert of Peptic Ulcer Disease

Peptic ulcer disease (PUD) is a common ailment that can feel like navigating a desert of discomfort and pain. This research, like a wellspring of hope, investigates the effectiveness of cimetidine in treating duodenal and prepyloric ulcers.

The study, conducted in a double-blind, randomized trial, compares the effects of cimetidine to placebo in patients with endoscopically confirmed duodenal and/or prepyloric ulcers. The findings demonstrate a significant improvement in ulcer healing and a reduction in pain symptoms in patients receiving cimetidine, offering a potential solution to the persistent discomfort of PUD.

A Beacon of Hope for Ulcer Sufferers

The study reveals that cimetidine is an effective treatment option for duodenal and prepyloric ulcers, showing a significant improvement in ulcer healing and a reduction in pain symptoms compared to placebo. It provides valuable insight into the potential of cimetidine in alleviating the burden of PUD.

Finding Relief in the Desert of Ulcer Pain

This research encourages individuals suffering from PUD to explore potential treatment options like cimetidine, which may provide a much-needed oasis in their journey towards relief. It highlights the importance of seeking medical advice for proper diagnosis and treatment of PUD.

Dr. Camel's Conclusion

This study offers a valuable insight into the effectiveness of cimetidine in treating duodenal and prepyloric ulcers, serving as a beacon of hope for those traversing the desert of PUD-related discomfort. It underscores the importance of seeking professional guidance in managing this condition effectively.

Date :
  1. Date Completed 1979-06-29
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

373260

DOI: Digital Object Identifier

373260

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Article Analysis
・Effects of cimetidine
SNS
PICO Info
in preparation
Languages

German

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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