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Drug-induced neutrophilic lobular panniculitis secondary to BRAF and MEK inhibitor used for treatment of low-grade glioma and its management.
Author: CavazosAnnia, FennerBlayne, MuiUyen, TarboxMichelle
Original Abstract of the Article :
An 8-year-old boy presented with his mother for evaluation of an erythematous rash 3 weeks after the start of dual BRAF-MEK inhibition with dabrafenib and trametinib for treatment of progression of low-grade glioma. Panniculitis has been reported as a rare adverse cutaneous event induced by BRAF inh...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10269401/
データ提供:米国国立医学図書館(NLM)
Navigating the Side Effects of Cancer Therapies: A Case Study
[Neutrophilic lobular panniculitis] is a rare but potentially serious [cutaneous side effect] that can occur as a result of [BRAF and MEK inhibitor therapy]. This case report describes the experience of an [8-year-old boy] who developed [neutrophilic lobular panniculitis] after receiving [dabrafenib and trametinib] for [low-grade glioma]. The authors highlight the importance of [early recognition and management] of such [side effects] to ensure [patient safety] and [treatment continuity]. They emphasize the need for [increased awareness] among healthcare providers about the [potential cutaneous manifestations] of [BRAF and MEK inhibitor therapy].
Managing Cancer Therapies: Balancing Benefits and Risks
This case report underscores the importance of carefully weighing the [benefits and risks] associated with [cancer therapies]. While [BRAF and MEK inhibitors] offer hope for patients with [low-grade glioma], it is essential to be aware of the [potential side effects]. This case serves as a reminder to [closely monitor patients] receiving these therapies and to [promptly address] any [adverse events] that may arise.
Open Communication and Patient Advocacy: Key to Successful Treatment
The findings of this case study emphasize the importance of [open communication] between [patients] and [healthcare providers]. By [openly discussing] any [concerns or side effects], patients can play an active role in [managing their treatment] and [ensuring their well-being]. Advocating for yourself is crucial to [receiving the best possible care] and [achieving the best possible outcomes].
Dr. Camel's Conclusion
Imagine a desert traveler battling a fierce sandstorm, seeking shelter and protection. Neutrophilic lobular panniculitis, like a sudden sandstorm, can disrupt the journey to recovery. This case report serves as a reminder to be vigilant, to seek shelter and protection from unexpected side effects, and to navigate the challenges of cancer treatment with courage and determination.
Date :
- Date Completed n.d.
- Date Revised 2023-06-20
Further Info :
Related Literature
English
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